Oliver H. Barker

97 Lisburn Road
Belfast, NIR BT97AE, United Kingdom

Last Updated: 09/26/2026

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Found 9 publications

Peri-operative Replacement of Exogenous Steroids (PREdS): a national audit of current peri-operative prescribing for patients taking therapeutic steroids.

Peri-operative Replacement of Exogenous Steroids (PREdS): a national audit of current peri-operative prescribing for patients taking therapeutic steroids.

Journal: Anaesthesia

Published: June 04, 2024

Identification and development of a subtype-selective allosteric AKT inhibitor suitable for clinical development.

Identification and development of a subtype-selective allosteric AKT inhibitor suitable for clinical development.

Journal: Scientific reports

Published: March 28, 2022

Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors.

Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors.

Journal: ACS medicinal chemistry letters

Published: December 08, 2017

Discovery and characterization of highly potent and selective allosteric USP7 inhibitors.

Discovery and characterization of highly potent and selective allosteric USP7 inhibitors.

Journal: Nature chemical biology

Published: February 27, 2017

Intermittent applied mechanical loading induces subchondral bone thickening that may be intensified locally by contiguous articular cartilage lesions.

Intermittent applied mechanical loading induces subchondral bone thickening that may be intensified locally by contiguous articular cartilage lesions.

Journal: Osteoarthritis and cartilage

Published: August 12, 2014

Binding mode and structure-activity relationships around direct inhibitors of the Nrf2-Keap1 complex.

Binding mode and structure-activity relationships around direct inhibitors of the Nrf2-Keap1 complex.

Journal: ChemMedChem

Published: December 13, 2013

Toward an understanding of agonist binding to human Orexin-1 and Orexin-2 receptors with G-protein-coupled receptor modeling and site-directed mutagenesis.

Toward an understanding of agonist binding to human Orexin-1 and Orexin-2 receptors with G-protein-coupled receptor modeling and site-directed mutagenesis.

Journal: Biochemistry

Published: October 23, 2013

Fighting obesity with a sugar-based library: discovery of novel MCH-1R antagonists by a new computational-VAST approach for exploration of GPCR binding sites.

Fighting obesity with a sugar-based library: discovery of novel MCH-1R antagonists by a new computational-VAST approach for exploration of GPCR binding sites.

Journal: Journal of chemical information and modeling

Published: April 18, 2013

Study of human Orexin-1 and -2 G-protein-coupled receptors with novel and published antagonists by modeling, molecular dynamics simulations, and site-directed mutagenesis.

Study of human Orexin-1 and -2 G-protein-coupled receptors with novel and published antagonists by modeling, molecular dynamics simulations, and site-directed mutagenesis.

Journal: Biochemistry

Published: March 28, 2012

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Last Updated: 09/26/2026