Olivier Bignucolo - Publications

SPARC: a structural pathogenicity algorithm for risk classification of hERG variants.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

Published: November 14, 2025

Efficacy and safety of eltrombopag in combination with dexamethasone as first-line treatment in adult patients with newly diagnosed immune thrombocytopenia.

Journal: British journal of haematology

Published: August 22, 2025

Molecular mechanisms and hotspots of pH sensing in ASIC1a revealed by computational and functional analysis.

Journal: Communications biology

Published: January 31, 2025

Identification of the modulatory Ca2+-binding sites of acid-sensing ion channel 1a.

Journal: Open biology

Published: June 19, 2024

Mechanistic basis of the dynamic response of TWIK1 ionic selectivity to pH.

Journal: Nature communications

Published: November 08, 2023

Case report: 'Atypical Richter transformation from CLL-type monoclonal B-cell lymphocytosis into Burkitt lymphoma in a treatment naïve patient'.

Journal: Frontiers in oncology

Published: September 18, 2023

Calcium regulates acid-sensing ion channel 3 activation by competing with protons in the channel pore and at an allosteric binding site.

Journal: Open biology

Published: December 21, 2022

Galvani Offset Potential and Constant-pH Simulations of Membrane Proteins.

Journal: The journal of physical chemistry. B

Published: September 01, 2022

Autoimmunity and immunodeficiency associated with monoallelic LIG4 mutations via haploinsufficiency.

Journal: The Journal of allergy and clinical immunology

Published: March 28, 2022

Kinetic analysis of ASIC1a delineates conformational signaling from proton-sensing domains to the channel gate.

Journal: eLife

Published: January 13, 2021

The Voltage-Dependent Deactivation of the KvAP Channel Involves the Breakage of Its S4 Helix.

Journal: Frontiers in molecular biosciences

Published: April 11, 2020

Structural and Functional Analysis of Gly212 Mutants Reveals the Importance of Intersubunit Interactions in ASIC1a Channel Function.

Journal: Frontiers in molecular biosciences

Published: February 12, 2020