Omaima M. Aboulwafa

Alexandria, ALX 21521, Egypt

Last Updated: 09/26/2026

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Found 17 publications

Novel benzoxazole-based hybrids as multi-target inhibitors of aromatase, EGFR, and PI3K with potential anti-breast cancer activity.

Novel benzoxazole-based hybrids as multi-target inhibitors of aromatase, EGFR, and PI3K with potential anti-breast cancer activity.

Journal: Bioorganic & medicinal chemistry

Published: September 19, 2025

Developing new anticancer agents: Design, synthesis, biological evaluation and in silico study of several functionalized pyrimidine-5-carbonitriles as small molecules modulators targeting breast cancer.

Developing new anticancer agents: Design, synthesis, biological evaluation and in silico study of several functionalized pyrimidine-5-carbonitriles as small molecules modulators targeting breast cancer.

Journal: Bioorganic chemistry

Published: October 08, 2024

Design, synthesis and molecular docking study of new pyrimidine-based hydrazones with selective anti-proliferative activity against MCF-7 and MDA-MB-231 human breast cancer cell lines.

Design, synthesis and molecular docking study of new pyrimidine-based hydrazones with selective anti-proliferative activity against MCF-7 and MDA-MB-231 human breast cancer cell lines.

Journal: Bioorganic chemistry

Published: March 15, 2023

Benzoxazole-appended piperidine derivatives as novel anticancer candidates against breast cancer.

Benzoxazole-appended piperidine derivatives as novel anticancer candidates against breast cancer.

Journal: Bioorganic chemistry

Published: November 07, 2022

New functionalized 6-thienylpyrimidine-5-carbonitriles as antiproliferative agents against human breast cancer cells.

New functionalized 6-thienylpyrimidine-5-carbonitriles as antiproliferative agents against human breast cancer cells.

Journal: Archiv der Pharmazie

Published: May 09, 2021

Design and Synthesis of Novel Quinazolinone-Based Oxobutanenitrile Derivatives as Antiproliferative Agents Targeting Human Breast Cancer.

Design and Synthesis of Novel Quinazolinone-Based Oxobutanenitrile Derivatives as Antiproliferative Agents Targeting Human Breast Cancer.

Journal: Anti-cancer agents in medicinal chemistry

Published: March 07, 2021

New thieno[3,2-d]pyrimidine-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents, EGFR and ARO inhibitors inducing apoptosis in breast cancer cells.

New thieno[3,2-d]pyrimidine-based derivatives: Design, synthesis and biological evaluation as antiproliferative agents, EGFR and ARO inhibitors inducing apoptosis in breast cancer cells.

Journal: Bioorganic chemistry

Published: February 20, 2021

Antiproliferative activity, enzymatic inhibition and apoptosis-promoting effects of benzoxazole-based hybrids on human breast cancer cells.

Antiproliferative activity, enzymatic inhibition and apoptosis-promoting effects of benzoxazole-based hybrids on human breast cancer cells.

Journal: Bioorganic chemistry

Published: August 21, 2020

Antiestrogenic Activity and Possible Mode of Action of Certain New Nonsteroidal Coumarin-4-acetamides.

Antiestrogenic Activity and Possible Mode of Action of Certain New Nonsteroidal Coumarin-4-acetamides.

Journal: Molecules (Basel, Switzerland)

Published: February 16, 2020

2-Anilinopyrimidine derivatives: Design, synthesis, in vitro anti-proliferative activity, EGFR and ARO inhibitory activity, cell cycle analysis and molecular docking study.

2-Anilinopyrimidine derivatives: Design, synthesis, in vitro anti-proliferative activity, EGFR and ARO inhibitory activity, cell cycle analysis and molecular docking study.

Journal: Bioorganic chemistry

Published: February 08, 2020

Benzoxazole derivatives as new generation of anti-breast cancer agents.

Benzoxazole derivatives as new generation of anti-breast cancer agents.

Journal: Bioorganic chemistry

Published: September 18, 2019

Design and synthesis of some β-carboline derivatives as multi-target anticancer agents.

Design and synthesis of some β-carboline derivatives as multi-target anticancer agents.

Journal: Future medicinal chemistry

Published: December 13, 2018

Showing 1-12 of 17

Last Updated: 09/26/2026