Osbaldo Charcas-Lopez

Tours, 37032, France

Last Updated: 09/26/2026

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Found 14 publications

Design, Synthesis, and Evaluation of Sodium Channel Blockers with Anti-invasive Activities in Medullary Thyroid Cancer.

Design, Synthesis, and Evaluation of Sodium Channel Blockers with Anti-invasive Activities in Medullary Thyroid Cancer.

Journal: ACS medicinal chemistry letters
Published: November 26, 2024

Blockade of CaV3 calcium channels and induction of G0/G1 cell cycle arrest in colon cancer cells by gossypol.

Blockade of CaV3 calcium channels and induction of G0/G1 cell cycle arrest in colon cancer cells by gossypol.

Journal: British journal of pharmacology
Published: October 05, 2023

Voltage-Gated Sodium Channel NaV1.5 Controls NHE-1-Dependent Invasive Properties in Colon Cancer Cells.

Voltage-Gated Sodium Channel NaV1.5 Controls NHE-1-Dependent Invasive Properties in Colon Cancer Cells.

Journal: Cancers
Published: November 05, 2022

Leveraging the ATP-P2X7 receptor signalling axis to alleviate traumatic CNS damage and related complications.

Leveraging the ATP-P2X7 receptor signalling axis to alleviate traumatic CNS damage and related complications.

Journal: Medicinal research reviews
Published: January 20, 2022

P2x4 receptor promotes mammary cancer progression by sustaining autophagy and associated mesenchymal transition.

P2x4 receptor promotes mammary cancer progression by sustaining autophagy and associated mesenchymal transition.

Journal: Oncogene
Published: September 21, 2021

The Voltage-Gated Sodium Channel Beta4 Subunit Maintains Epithelial Phenotype in Mammary Cells.

The Voltage-Gated Sodium Channel Beta4 Subunit Maintains Epithelial Phenotype in Mammary Cells.

Journal: Cells
Published: May 21, 2021

Pharmacological and nutritional targeting of voltage-gated sodium channels in the treatment of cancers.

Pharmacological and nutritional targeting of voltage-gated sodium channels in the treatment of cancers.

Journal: iScience
Published: April 05, 2021

P2X7 Receptor Promotes Mouse Mammary Cancer Cell Invasiveness and Tumour Progression, and Is a Target for Anticancer Treatment.

P2X7 Receptor Promotes Mouse Mammary Cancer Cell Invasiveness and Tumour Progression, and Is a Target for Anticancer Treatment.

Journal: Cancers
Published: July 08, 2020

Rock inhibition promotes NaV1.5 sodium channel-dependent SW620 colon cancer cell invasiveness.

Rock inhibition promotes NaV1.5 sodium channel-dependent SW620 colon cancer cell invasiveness.

Journal: Scientific reports
Published: April 01, 2020

Sodium Channel Nav1.5 Controls Epithelial-to-Mesenchymal Transition and Invasiveness in Breast Cancer Cells Through its Regulation by the Salt-Inducible Kinase-1.

Sodium Channel Nav1.5 Controls Epithelial-to-Mesenchymal Transition and Invasiveness in Breast Cancer Cells Through its Regulation by the Salt-Inducible Kinase-1.

Journal: Scientific reports
Published: July 23, 2019

The invasiveness of human cervical cancer associated to the function of NaV1.6 channels is mediated by MMP-2 activity.

The invasiveness of human cervical cancer associated to the function of NaV1.6 channels is mediated by MMP-2 activity.

Journal: Scientific reports
Published: April 06, 2018

Discovery and evaluation of nNav1.5 sodium channel blockers with potent cell invasion inhibitory activity in breast cancer cells.

Discovery and evaluation of nNav1.5 sodium channel blockers with potent cell invasion inhibitory activity in breast cancer cells.

Journal: Bioorganic & medicinal chemistry
Published: November 20, 2017
Showing 1-12 of 14

Last Updated: 09/26/2026