Oscar M. Aguilera-Bautista
Alcala De Henares, MD 28805, Spain
Last Updated: 09/26/2026
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Found 19 publications
N-Methyl-N-((1-methyl-5-(3-(piperidin-1-yl)propoxy)-1H-benzo[d]imidazol-2-yl)methyl)prop-2-yn-1-amine (MBA-159), a new multitarget small molecule for the therapy of Alzheimer's disease.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: May 28, 2025
Contilisant+Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-Based Multitarget Small Molecules with In Vitro and In Vivo Activity in Neurodegenerative Diseases.
Journal: Journal of medicinal chemistry
Published: September 10, 2024
N-Hydroxy-N-Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases.
Journal: Molecules (Basel, Switzerland)
Published: October 04, 2022
In Vitro and In Silico ADME-Tox Profiling and Safety Significance of Multifunctional Monoamine Oxidase Inhibitors Targeting Neurodegenerative Diseases.
Journal: ACS chemical neuroscience
Published: November 04, 2020
Tacrines as Therapeutic Agents for Alzheimer's Disease. V. Recent Developments.
Journal: Chemical record (New York, N.Y.)
Published: September 04, 2020
Triazolopyridopyrimidine: A New Scaffold for Dual-Target Small Molecules for Alzheimer's Disease Therapy.
Journal: Molecules (Basel, Switzerland)
Published: June 22, 2020
Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer's Disease Therapy.
Journal: International journal of molecular sciences
Published: April 10, 2020
Contilisant, a Tetratarget Small Molecule for Alzheimer's Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition, and H3R Antagonism with S1R Agonism Profile.
Journal: Journal of medicinal chemistry
Published: July 04, 2018
Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3 R Antagonism for Neurodegenerative Diseases.
Journal: Angewandte Chemie (International ed. in English)
Published: June 14, 2017
The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators.
Journal: Journal of medicinal chemistry
Published: October 14, 2016
N-Benzylpiperidine Derivatives as α7 Nicotinic Receptor Antagonists.
Journal: ACS chemical neuroscience
Published: June 03, 2016
Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer's Disease.
Journal: Molecules (Basel, Switzerland)
Published: February 18, 2016
Last Updated: 09/26/2026