Osvaldo A. Filho-Santos
Rio De Janeiro, RJ 21941902, Brazil
Last Updated: 09/26/2026
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Found 20 publications
Cross-Species Hepatic Metabolism of the Antileishmanial Chalcone NAT22 Generates Metabolites with Predicted Enhanced Affinity for the Parasite Target cTXNPx.
Journal: Pharmaceutics
Published: March 01, 2026
Ruthenium Complexes Containing Thiobenzamide Act as Potent and Selective Anti-Trypanosoma cruzi Agents through Apoptotic Cell Death.
Journal: ACS infectious diseases
Published: January 08, 2026
In silico and in vitro investigation of the safety and immunomodulatory mechanisms of 7-hydroxyflavone.
Journal: Chemico-biological interactions
Published: November 16, 2025
Exploring Experimental and In Silico Approaches for Antibody-Drug Conjugates in Oncology Therapies.
Journal: Pharmaceuticals (Basel, Switzerland)
Published: July 03, 2025
The Alkaloid Caulerpin Exhibits Potent and Selective Anti-Inflammatory Activity Through Interaction with the Glucocorticoid Receptor.
Journal: Marine drugs
Published: May 03, 2025
In silico, in vitro, and in vivo assessment of anti-Trypanosoma cruzi activity of the 1H-indazole-containing ruthenium complex FOR0E2.
Journal: Acta tropica
Published: February 06, 2025
Solidagenone from Solidago chilensis Meyen Protects against Acute Peritonitis and Lipopolysaccharide-Induced Shock by Regulating NF-κB Signaling Pathway.
Journal: Pharmaceuticals (Basel, Switzerland)
Published: December 28, 2023
Synthesis and evaluation of hybrid sulfonamide-chalcones with potential antileishmanial activity.
Journal: Archiv der Pharmazie
Published: August 09, 2023
Aurones: A Promising Scaffold to Inhibit SARS-CoV-2 Replication.
Journal: Journal of natural products
Published: May 31, 2023
Identification of Potential Allosteric Site Binders of Indoleamine 2,3-Dioxygenase 1 from Plants: A Virtual and Molecular Dynamics Investigation.
Journal: Pharmaceuticals (Basel, Switzerland)
Published: July 13, 2022
Geissoschizoline, a promising alkaloid for Alzheimer's disease: Inhibition of human cholinesterases, anti-inflammatory effects and molecular docking.
Journal: Bioorganic chemistry
Published: May 30, 2020
Pharmacological profiling of JME-173, a novel mexiletine derivative combining dual anti-inflammatory/anti-spasmodic functions and limited action in Na+ channels.
Journal: European journal of pharmacology
Published: May 15, 2020
Last Updated: 09/26/2026