Ottilia Balazs

30-32 Gyömrői Street
Budapest, BU 1103, Hungary

Last Updated: 09/26/2026

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Found 11 publications

The Discovery of RGH-706, a Highly Efficacious MCH1 Receptor Antagonist, for the Treatment of Obesity and Insatiable Hunger.

The Discovery of RGH-706, a Highly Efficacious MCH1 Receptor Antagonist, for the Treatment of Obesity and Insatiable Hunger.

Journal: Journal of medicinal chemistry

Published: January 22, 2026

Discovery of Novel Steroid-Based Histamine H3 Receptor Antagonists/Inverse Agonists.

Discovery of Novel Steroid-Based Histamine H3 Receptor Antagonists/Inverse Agonists.

Journal: Journal of medicinal chemistry

Published: February 23, 2024

Optimization of Novel α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulators and the Discovery of a Preclinical Development Candidate Molecule (RGH-560).

Optimization of Novel α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulators and the Discovery of a Preclinical Development Candidate Molecule (RGH-560).

Journal: Journal of medicinal chemistry

Published: November 21, 2023

Convergent cross-species pro-cognitive effects of RGH-235, a new potent and selective histamine H3 receptor antagonist/inverse agonist.

Convergent cross-species pro-cognitive effects of RGH-235, a new potent and selective histamine H3 receptor antagonist/inverse agonist.

Journal: European journal of pharmacology

Published: May 07, 2021

HTS-based discovery and optimization of novel positive allosteric modulators of the α7 nicotinic acetylcholine receptor.

HTS-based discovery and optimization of novel positive allosteric modulators of the α7 nicotinic acetylcholine receptor.

Journal: European journal of medicinal chemistry

Published: February 26, 2021

Cariprazine modulates sleep architecture in rats.

Cariprazine modulates sleep architecture in rats.

Journal: Journal of psychopharmacology (Oxford, England)

Published: January 07, 2021

Discovery of novel positive allosteric modulators of the α7 nicotinic acetylcholine receptor: Scaffold hopping approach.

Discovery of novel positive allosteric modulators of the α7 nicotinic acetylcholine receptor: Scaffold hopping approach.

Journal: European journal of medicinal chemistry

Published: October 08, 2020

Discovery of novel steroidal histamine H3 receptor antagonists/inverse agonists. Part 2. Versatile steroidal carboxamide derivatives.

Discovery of novel steroidal histamine H3 receptor antagonists/inverse agonists. Part 2. Versatile steroidal carboxamide derivatives.

Journal: Bioorganic & medicinal chemistry letters

Published: May 22, 2019

Preclinical pharmacodynamic and pharmacokinetic characterization of the major metabolites of cariprazine.

Preclinical pharmacodynamic and pharmacokinetic characterization of the major metabolites of cariprazine.

Journal: Drug design, development and therapy

Published: September 26, 2018

Discovery of novel steroidal histamine H3 receptor antagonists/inverse agonists.

Discovery of novel steroidal histamine H3 receptor antagonists/inverse agonists.

Journal: Bioorganic & medicinal chemistry letters

Published: July 03, 2017

Discovery and Preclinical Characterization of 3-((4-(4-Chlorophenyl)-7-fluoroquinoline-3-yl)sulfonyl)benzonitrile, a Novel Non-acetylenic Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulator for Psychiatric Indications.

Discovery and Preclinical Characterization of 3-((4-(4-Chlorophenyl)-7-fluoroquinoline-3-yl)sulfonyl)benzonitrile, a Novel Non-acetylenic Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulator for Psychiatric Indications.

Journal: Journal of medicinal chemistry

Published: February 18, 2017

Showing 1-11 of 11

Last Updated: 09/26/2026