Panagis Filippakopoulos

Old Road Campus Research Building, Roosevelt Drive
Oxford, ENG OX37DQ, United Kingdom

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 73 publications

Water Networks as Hydrophobic Recognition Motifs in Proteins.

Water Networks as Hydrophobic Recognition Motifs in Proteins.

Journal: Angewandte Chemie (International ed. in English)

Published: September 25, 2025

Proteasome Cap Targeting Chimeras for Ubiquitination-Independent Targeted Protein Degradation.

Proteasome Cap Targeting Chimeras for Ubiquitination-Independent Targeted Protein Degradation.

Journal: Angewandte Chemie (International ed. in English)

Published: September 11, 2025

Histone H4K16ac Binding Function of the Triple PHD Finger Cassette of MLL4.

Histone H4K16ac Binding Function of the Triple PHD Finger Cassette of MLL4.

Journal: Journal of molecular biology

Published: April 17, 2023

Discovery of Benzo[d]imidazole-6-sulfonamides as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain.

Discovery of Benzo[d]imidazole-6-sulfonamides as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain.

Journal: ChemMedChem

Published: June 27, 2022

Acetylation reprograms MITF target selectivity and residence time.

Acetylation reprograms MITF target selectivity and residence time.

Journal: Nature communications

Published: February 02, 2022

Discovery of Novel BRD4 Ligand Scaffolds by Automated Navigation of the Fragment Chemical Space.

Discovery of Novel BRD4 Ligand Scaffolds by Automated Navigation of the Fragment Chemical Space.

Journal: Journal of medicinal chemistry

Published: December 13, 2021

Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain.

Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain.

Journal: Journal of medicinal chemistry

Published: July 13, 2021

The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif.

The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif.

Journal: PloS one

Published: May 06, 2021

Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression.

Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression.

Journal: ACS central science

Published: January 15, 2021

Editorial: Structural Studies of Protein Complexes in Signaling Pathways.

Editorial: Structural Studies of Protein Complexes in Signaling Pathways.

Journal: Frontiers in molecular biosciences

Published: December 15, 2020

Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function.

Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function.

Journal: Frontiers in immunology

Published: November 05, 2020

BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation.

BRD4 methylation by the methyltransferase SETD6 regulates selective transcription to control mRNA translation.

Journal: Science advances

Published: November 02, 2020

Showing 1-12 of 73

Last Updated: 09/26/2026