Paola Storici

5 In AREA Science Park
Trieste, 34149, Italy

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 42 publications

A Polypharmacology-Driven Approach to Alzheimer's Disease and Tauopathies: Rational Design, Synthesis and Characterization of Amino-Pyrazole-Based Multikinase (GSK-3β/FYN-α/DYRK1A) Inhibitors.

A Polypharmacology-Driven Approach to Alzheimer's Disease and Tauopathies: Rational Design, Synthesis and Characterization of Amino-Pyrazole-Based Multikinase (GSK-3β/FYN-α/DYRK1A) Inhibitors.

Journal: Journal of medicinal chemistry

Published: April 29, 2026

Discovery of a new selective ERAP1 inhibitor for Hedgehog-dependent cancer treatment.

Discovery of a new selective ERAP1 inhibitor for Hedgehog-dependent cancer treatment.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: April 11, 2025

FL30: an epidermal growth factor kinase inhibitor overcoming T790M and C797S mutations through unique conformational modulation mechanism.

FL30: an epidermal growth factor kinase inhibitor overcoming T790M and C797S mutations through unique conformational modulation mechanism.

Journal: International journal of biological macromolecules

Published: March 26, 2025

Rational optimization of D3R/GSK-3β dual target-directed ligands as potential treatment for bipolar disorder: Design, synthesis, X-ray crystallography, molecular dynamics simulations, in vitro ADME, and in vivo pharmacokinetic studies.

Rational optimization of D3R/GSK-3β dual target-directed ligands as potential treatment for bipolar disorder: Design, synthesis, X-ray crystallography, molecular dynamics simulations, in vitro ADME, and in vivo pharmacokinetic studies.

Journal: European journal of medicinal chemistry

Published: March 03, 2025

Macromolecular crystallography at Elettra: current and future perspectives. Corrigendum.

Macromolecular crystallography at Elettra: current and future perspectives. Corrigendum.

Journal: Journal of synchrotron radiation

Published: December 04, 2024

Macromolecular crystallography at Elettra: current and future perspectives.

Macromolecular crystallography at Elettra: current and future perspectives.

Journal: Journal of synchrotron radiation

Published: December 04, 2024

Cys44 of SARS-CoV-2 3CLpro affects its catalytic activity.

Cys44 of SARS-CoV-2 3CLpro affects its catalytic activity.

Journal: International journal of biological macromolecules

Published: September 05, 2024

Probing conformational dynamics of EGFR mutants via SEIRA spectroscopy: potential implications for tyrosine kinase inhibitor design.

Probing conformational dynamics of EGFR mutants via SEIRA spectroscopy: potential implications for tyrosine kinase inhibitor design.

Journal: Physical chemistry chemical physics : PCCP

Published: August 23, 2024

Thiol-Reactive or Redox-Active: Revising a Repurposing Screen Led to a New Invalidation Pipeline and Identified a True Noncovalent Inhibitor Against Papain-like Protease from SARS-CoV-2.

Thiol-Reactive or Redox-Active: Revising a Repurposing Screen Led to a New Invalidation Pipeline and Identified a True Noncovalent Inhibitor Against Papain-like Protease from SARS-CoV-2.

Journal: ACS pharmacology & translational science

Published: May 31, 2024

Unexpected Single-Ligand Occupancy and Negative Cooperativity in the SARS-CoV-2 Main Protease.

Unexpected Single-Ligand Occupancy and Negative Cooperativity in the SARS-CoV-2 Main Protease.

Journal: Journal of chemical information and modeling

Published: December 05, 2023

Identification of additional mechanistically important residues in the multidrug transporter styMdtM of Salmonella Typhi.

Identification of additional mechanistically important residues in the multidrug transporter styMdtM of Salmonella Typhi.

Journal: Journal of biomolecular structure & dynamics

Published: October 03, 2023

Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination.

Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination.

Journal: European journal of medicinal chemistry

Published: December 13, 2022

Showing 1-12 of 42

Last Updated: 09/26/2026