Parimala R. Vajjhala

Brisbane, QLD, Australia

Last Updated: 09/26/2026

Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 18 publications

Dengue virus NS1 protein does not activate TLR4 and has a modest effect on endothelial monolayer integrity compared to TNF.

Dengue virus NS1 protein does not activate TLR4 and has a modest effect on endothelial monolayer integrity compared to TNF.

Journal: PLoS pathogens
Published: April 03, 2025

Structural basis for TIR domain-mediated innate immune signaling by Toll-like receptor adaptors TRIF and TRAM.

Structural basis for TIR domain-mediated innate immune signaling by Toll-like receptor adaptors TRIF and TRAM.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: January 09, 2025

o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2.

o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2.

Journal: Journal of enzyme inhibition and medicinal chemistry
Published: February 28, 2024

Kinetics of severe dengue virus infection and development of gut pathology in mice.

Kinetics of severe dengue virus infection and development of gut pathology in mice.

Journal: Journal of virology
Published: October 18, 2023

TLR4 phosphorylation at tyrosine 672 activates the ERK/c-FOS signaling module for LPS-induced cytokine responses in macrophages.

TLR4 phosphorylation at tyrosine 672 activates the ERK/c-FOS signaling module for LPS-induced cytokine responses in macrophages.

Journal: European journal of immunology
Published: June 20, 2022

Flow cytometric reporter assays provide robust functional analysis of signaling complexes.

Flow cytometric reporter assays provide robust functional analysis of signaling complexes.

Journal: The Journal of biological chemistry
Published: February 17, 2022

MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography.

MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography.

Journal: Nature communications
Published: December 24, 2020

Caspase-1 Is an Apical Caspase Leading to Caspase-3 Cleavage in the AIM2 Inflammasome Response, Independent of Caspase-8.

Caspase-1 Is an Apical Caspase Leading to Caspase-3 Cleavage in the AIM2 Inflammasome Response, Independent of Caspase-8.

Journal: Journal of molecular biology
Published: February 03, 2017

Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling.

Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling.

Journal: Nature structural & molecular biology
Published: January 30, 2017

The molecular mechanisms of signaling by cooperative assembly formation in innate immunity pathways.

The molecular mechanisms of signaling by cooperative assembly formation in innate immunity pathways.

Journal: Molecular immunology
Published: January 12, 2017

Assessment of Inflammasome Formation by Flow Cytometry.

Assessment of Inflammasome Formation by Flow Cytometry.

Journal: Current protocols in immunology
Published: August 02, 2016

Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex.

Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex.

Journal: Molecular cell
Published: June 24, 2016
Showing 1-12 of 18

Last Updated: 09/26/2026