Patricia B. Da Silva

Rio De Janeiro, RJ, Brazil

Last Updated: 09/26/2026

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Found 20 publications

Cafestol and kahweol: coffee diterpenes with trypanocidal activity and cardioprotective effects.

Cafestol and kahweol: coffee diterpenes with trypanocidal activity and cardioprotective effects.

Journal: Frontiers in cellular and infection microbiology

Published: May 19, 2026

In Vitro Phenotypic Activity and In Silico Analysis of Natural Products from Brazilian Biodiversity on Trypanosoma cruzi.

In Vitro Phenotypic Activity and In Silico Analysis of Natural Products from Brazilian Biodiversity on Trypanosoma cruzi.

Journal: Molecules (Basel, Switzerland)

Published: June 24, 2021

Characterization and trypanocidal activity of a β-lapachone-containing drug carrier.

Characterization and trypanocidal activity of a β-lapachone-containing drug carrier.

Journal: PloS one

Published: September 22, 2020

Copper(II) complex-loaded castor oil-based nanostructured lipid carriers used against Mycobacterium tuberculosis : Development, characterisation, in vitro and in vivo biological assays.

Copper(II) complex-loaded castor oil-based nanostructured lipid carriers used against Mycobacterium tuberculosis : Development, characterisation, in vitro and in vivo biological assays.

Journal: Die Pharmazie

Published: January 08, 2020

Evaluation of phthalazinone phosphodiesterase inhibitors with improved activity and selectivity against Trypanosoma cruzi.

Evaluation of phthalazinone phosphodiesterase inhibitors with improved activity and selectivity against Trypanosoma cruzi.

Journal: The Journal of antimicrobial chemotherapy

Published: July 19, 2019

Repurposing strategies for Chagas disease therapy: the effect of imatinib and derivatives against Trypanosoma cruzi.

Repurposing strategies for Chagas disease therapy: the effect of imatinib and derivatives against Trypanosoma cruzi.

Journal: Parasitology

Published: March 13, 2019

New 1,2,3-triazole-based analogues of benznidazole for use against Trypanosoma cruzi infection: In vitro and in vivo evaluations.

New 1,2,3-triazole-based analogues of benznidazole for use against Trypanosoma cruzi infection: In vitro and in vivo evaluations.

Journal: Chemical biology & drug design

Published: February 20, 2018

Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2-Benzyl-5-nitroindazole-Derived Amines.

Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2-Benzyl-5-nitroindazole-Derived Amines.

Journal: ChemMedChem

Published: February 08, 2018

Identification of Pyrazolo[3,4-e][1,4]thiazepin based CYP51 inhibitors as potential Chagas disease therapeutic alternative: In vitro and in vivo evaluation, binding mode prediction and SAR exploration.

Identification of Pyrazolo[3,4-e][1,4]thiazepin based CYP51 inhibitors as potential Chagas disease therapeutic alternative: In vitro and in vivo evaluation, binding mode prediction and SAR exploration.

Journal: European journal of medicinal chemistry

Published: December 19, 2017

In Vitro, In Silico, and In Vivo Analyses of Novel Aromatic Amidines against Trypanosoma cruzi.

In Vitro, In Silico, and In Vivo Analyses of Novel Aromatic Amidines against Trypanosoma cruzi.

Journal: Antimicrobial agents and chemotherapy

Published: October 26, 2017

In Vitro and In Vivo Studies of the Trypanocidal Effect of Novel Quinolines.

In Vitro and In Vivo Studies of the Trypanocidal Effect of Novel Quinolines.

Journal: Antimicrobial agents and chemotherapy

Published: September 15, 2017

Drug repurposing strategy against Trypanosoma cruzi infection: In vitro and in vivo assessment of the activity of metronidazole in mono- and combined therapy.

Drug repurposing strategy against Trypanosoma cruzi infection: In vitro and in vivo assessment of the activity of metronidazole in mono- and combined therapy.

Journal: Biochemical pharmacology

Published: June 16, 2017

Showing 1-12 of 20

Last Updated: 09/26/2026