Patricia Umlandt - Publications

Haploinsufficiency of miR-143 and miR-145 reveal targetable dependencies in resistant del(5q) myelodysplastic neoplasm.

Journal: Leukemia

Published: April 28, 2024

TIRAP drives myelosuppression through an Ifnγ-Hmgb1 axis that disrupts the endothelial niche in mice.

Journal: The Journal of experimental medicine

Published: April 16, 2020

Loss of lenalidomide-induced megakaryocytic differentiation leads to therapy resistance in del(5q) myelodysplastic syndrome.

Journal: Nature cell biology

Published: March 26, 2019

miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling.

Journal: Nature communications

Published: May 17, 2017

Endothelial Sash1 Is Required for Lung Maturation through Nitric Oxide Signaling.

Journal: Cell reports

Published: March 03, 2017

Characterization of Clostridium difficile Strains in British Columbia, Canada: A Shift from NAP1 Majority (2008) to Novel Strain Types (2013) in One Region.

Journal: The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale

Published: August 28, 2015

A novel population of local pericyte precursor cells in tumor stroma that require Notch signaling for differentiation.

Journal: Microvascular research

Published: March 10, 2015

A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis.

Journal: Blood

Published: May 08, 2014

Endothelial-specific Notch blockade inhibits vascular function and tumor growth through an eNOS-dependent mechanism.

Journal: Cancer research

Published: March 07, 2014

A Notch-dependent transcriptional hierarchy promotes mesenchymal transdifferentiation in the cardiac cushion.

Journal: Developmental dynamics : an official publication of the American Association of Anatomists

Published: January 21, 2014