Patrick Chan-Sin
Toronto, ON M5G0A4, Canada
Last Updated: 09/26/2026
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Found 11 publications
A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor.
Journal: Cancer cell
Published: February 11, 2019
Molecular Classification and Management of Rare Pediatric Embryonal Brain Tumors.
Journal: Current oncology reports
Published: July 12, 2018
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling.
Journal: Nature
Published: December 19, 2016
Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis.
Journal: The Lancet. Oncology
Published: April 18, 2015
DNMTs as potential therapeutic targets in high-risk pediatric embryonal brain tumors.
Journal: Expert opinion on therapeutic targets
Published: August 22, 2014
CNS-PNETs with C19MC amplification and/or LIN28 expression comprise a distinct histogenetic diagnostic and therapeutic entity.
Journal: Acta neuropathologica
Published: November 26, 2013
Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR.
Journal: Nature genetics
Published: June 15, 2013
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy.
Journal: Nature
Published: March 10, 2013
Showing 1-11 of 11
Last Updated: 09/26/2026