Patrick Ernst
Zurich, ZH, Switzerland
Last Updated: 09/26/2026
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Found 19 publications
A nucleotide-independent, pan-RAS-targeted DARPin elicits anti-tumor activity in a multimodal manner.
Journal: Molecular oncology
Published: November 13, 2024
Modular binder technology by NGS-aided, high-resolution selection in yeast of designed armadillo modules.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: June 25, 2024
Unexpected dynamics in femtomolar complexes of binding proteins with peptides.
Journal: Nature communications
Published: February 18, 2023
Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Journal: Nature communications
Published: January 25, 2021
Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism.
Journal: Science advances
Published: August 29, 2020
Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action.
Journal: Nature communications
Published: July 04, 2020
Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.
Journal: ACS chemical biology
Published: January 28, 2020
Chaperone-assisted structure elucidation with DARPins.
Journal: Current opinion in structural biology
Published: August 30, 2019
Structural analysis of biological targets by host:guest crystal lattice engineering.
Journal: Scientific reports
Published: August 15, 2019
Last Updated: 09/26/2026