Patrick M. Sexton
Parkville, VIC, Australia
Last Updated: 09/26/2026
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Found 227 publications
Tools to investigate class B1 GPCR conformational landscapes with cryo-EM and beyond.
Journal: Biochemical Society transactions
Published: July 02, 2026
In vivo functional profiling and structural characterization of the human GLP1R A316T variant.
Journal: Science advances
Published: February 04, 2026
In vitro pharmacological profile of the TSH receptor-stimulating autoantibodies, M22 and K1-18.
Journal: Biochemical pharmacology
Published: January 27, 2026
Structural basis of modified ligand selectivity from N-terminal PAC1R alternative splicing.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: November 20, 2025
Native adenosine A2A receptor solubilisation by a library of amphipathic copolymers.
Journal: Biomaterials science
Published: October 27, 2025
Dynamics of the PAC1 receptor in apo, peptide agonist-bound, and G protein complexed states.
Journal: Structure (London, England : 1993)
Published: September 09, 2025
Design of peptide-based PAC1 antagonists combining molecular dynamics simulations and a biologically relevant cell-based assay.
Journal: bioRxiv : the preprint server for biology
Published: June 26, 2025
De novo design of miniprotein agonists and antagonists targeting G protein-coupled receptors.
Journal: bioRxiv : the preprint server for biology
Published: June 12, 2025
Design of peptide-based PAC1 antagonists combining molecular dynamics simulations and a biologically relevant cell-based assay.
Journal: Biochemical pharmacology
Published: May 29, 2025
Unique Biased Agonism Profile of βCGRP on CGRP Family Receptors.
Journal: Biochemistry
Published: May 27, 2025
Contrasting roles for GLP-1R and GIPR in a model of diet-induced obesity.
Journal: Journal of molecular endocrinology
Published: April 14, 2025
Last Updated: 09/26/2026