Patrik Oleksak

Hradec Kralove, KR 50003, Czech Republic

Last Updated: 09/26/2026

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Found 33 publications

The structure-activity relationship study of torkinib derivatives as mTOR inhibitors with senolytic and STAT3 inhibitory activities.

The structure-activity relationship study of torkinib derivatives as mTOR inhibitors with senolytic and STAT3 inhibitory activities.

Journal: Bioorganic chemistry

Published: January 14, 2026

In silico screening, synthesis, and biological evaluation of pyrazolopyrimidine-derived mTOR inhibitors for anticancer and senomorphic effects.

In silico screening, synthesis, and biological evaluation of pyrazolopyrimidine-derived mTOR inhibitors for anticancer and senomorphic effects.

Journal: Cancer cell international

Published: September 05, 2025

Clinical Significance of HBOT in Hypoxia-Induced Pathophysiological Conditions: A Comprehensive Investigative Study.

Clinical Significance of HBOT in Hypoxia-Induced Pathophysiological Conditions: A Comprehensive Investigative Study.

Journal: Current medicinal chemistry

Published: June 16, 2025

Erratum to "Frentizole derivatives with mTOR inhibiting and senomorphic properties" [Biomed. Pharmacother. 167 (2023) 115600].

Erratum to "Frentizole derivatives with mTOR inhibiting and senomorphic properties" [Biomed. Pharmacother. 167 (2023) 115600].

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: February 09, 2025

Comprehensive Assessment of Overactive Bladder (OAB) Treatment: Balancing Efficacy, Side Effects, and Quality of Life.

Comprehensive Assessment of Overactive Bladder (OAB) Treatment: Balancing Efficacy, Side Effects, and Quality of Life.

Journal: Current medicinal chemistry

Published: December 05, 2024

Corrigendum: Traditional uses, phytochemistry, pharmacology and toxicology of garlic (Allium sativum), a storehouse of diverse phytochemicals: a review of research from the last decade focusing on health and nutritional implications.

Corrigendum: Traditional uses, phytochemistry, pharmacology and toxicology of garlic (Allium sativum), a storehouse of diverse phytochemicals: a review of research from the last decade focusing on health and nutritional implications.

Journal: Frontiers in nutrition

Published: May 24, 2024

Discovery of a 6-Aminobenzo[b]thiophene 1,1-Dioxide Derivative (K2071) with a Signal Transducer and Activator of Transcription 3 Inhibitory, Antimitotic, and Senotherapeutic Activities.

Discovery of a 6-Aminobenzo[b]thiophene 1,1-Dioxide Derivative (K2071) with a Signal Transducer and Activator of Transcription 3 Inhibitory, Antimitotic, and Senotherapeutic Activities.

Journal: ACS pharmacology & translational science

Published: April 02, 2024

Anticholinesterases Traits Inbuilt in Buxaceae Plant Extracts against Alzheimer's Disease.

Anticholinesterases Traits Inbuilt in Buxaceae Plant Extracts against Alzheimer's Disease.

Journal: Current neuropharmacology

Published: February 29, 2024

Comprehensive analysis of prohibited substances and methods in sports: Unveiling trends, pharmacokinetics, and WADA evolution.

Comprehensive analysis of prohibited substances and methods in sports: Unveiling trends, pharmacokinetics, and WADA evolution.

Journal: Environmental toxicology and pharmacology

Published: November 28, 2023

Dendrobine: A neuroprotective Sesquiterpenic Alkaloid for the Prevention and Treatment of Diseases: A Review.

Dendrobine: A neuroprotective Sesquiterpenic Alkaloid for the Prevention and Treatment of Diseases: A Review.

Journal: Mini reviews in medicinal chemistry

Published: July 26, 2023

Targeted Inhibition of the PI3K/Akt/mTOR Signaling Axis: Potential for Sarcoma Therapy.

Targeted Inhibition of the PI3K/Akt/mTOR Signaling Axis: Potential for Sarcoma Therapy.

Journal: Mini reviews in medicinal chemistry

Published: July 06, 2023

Frentizole derivatives with mTOR inhibiting and senomorphic properties.

Frentizole derivatives with mTOR inhibiting and senomorphic properties.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: July 04, 2023

Showing 1-12 of 33

Last Updated: 09/26/2026