Last Updated: 09/26/2026
Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 24 publications
Expanding Addressable KRAS Mutations through the Structure- and Property-Based Design of Dual-State (GDP/GTP), Reversible Pan-KRAS Inhibitors.
Journal: Journal of medicinal chemistry
Published: July 14, 2026
Discovery of AMG 193, an MTA-Cooperative PRMT5 Inhibitor for the Treatment of MTAP-Deleted Cancers.
Journal: Journal of medicinal chemistry
Published: March 27, 2025
LKB1 regulates JNK-dependent stress signaling and apoptotic dependency of KRAS-mutant lung cancers.
Journal: Nature communications
Published: January 15, 2025
AMG 193, a Clinical Stage MTA-Cooperative PRMT5 Inhibitor, Drives Antitumor Activity Preclinically and in Patients with MTAP-Deleted Cancers.
Journal: Cancer discovery
Published: June 24, 2024
Correction: Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics.
Journal: Blood cancer journal
Published: May 16, 2023
Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition.
Journal: The EMBO journal
Published: May 01, 2023
Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics.
Journal: Blood cancer journal
Published: December 13, 2022
Maximal Activation of Apoptosis Signaling by Cotargeting Antiapoptotic Proteins in BH3 Mimetic-Resistant AML and AML Stem Cells.
Journal: Molecular cancer therapeutics
Published: August 11, 2021
AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: July 21, 2020
Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring an α-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere.
Journal: Journal of medicinal chemistry
Published: November 19, 2019
Targeting MCL-1 in hematologic malignancies: Rationale and progress.
Journal: Blood reviews
Published: September 18, 2019
Last Updated: 09/26/2026