Paul M. Wijnker

Amsterdam, NH 1081HZ, Netherlands

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 23 publications

Hypertrophic cardiomyopathy dysfunction mimicked in human engineered heart tissue and improved by sodium-glucose cotransporter 2 inhibitors.

Hypertrophic cardiomyopathy dysfunction mimicked in human engineered heart tissue and improved by sodium-glucose cotransporter 2 inhibitors.

Journal: Cardiovascular research

Published: December 01, 2022

Low expression of the K280N TNNT2 mutation is sufficient to increase basal myofilament activation in human hypertrophy cardiomyopathy.

Low expression of the K280N TNNT2 mutation is sufficient to increase basal myofilament activation in human hypertrophy cardiomyopathy.

Journal: Journal of molecular and cellular cardiology plus

Published: March 31, 2022

Development of a 3-Dimensional Model to Study Right Heart Dysfunction in Pulmonary Arterial Hypertension: First Observations.

Development of a 3-Dimensional Model to Study Right Heart Dysfunction in Pulmonary Arterial Hypertension: First Observations.

Journal: Cells

Published: August 26, 2021

Translational investigation of electrophysiology in hypertrophic cardiomyopathy.

Translational investigation of electrophysiology in hypertrophic cardiomyopathy.

Journal: Journal of molecular and cellular cardiology

Published: March 10, 2021

Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes.

Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes.

Journal: Cell stem cell

Published: February 24, 2020

Mutation-specific pathology and treatment of hypertrophic cardiomyopathy in patients, mouse models and human engineered heart tissue.

Mutation-specific pathology and treatment of hypertrophic cardiomyopathy in patients, mouse models and human engineered heart tissue.

Journal: Biochimica et biophysica acta. Molecular basis of disease

Published: November 29, 2019

Phosphomimetic cardiac myosin-binding protein C partially rescues a cardiomyopathy phenotype in murine engineered heart tissue.

Phosphomimetic cardiac myosin-binding protein C partially rescues a cardiomyopathy phenotype in murine engineered heart tissue.

Journal: Scientific reports

Published: September 11, 2019

The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM.

The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM.

Journal: The Journal of general physiology

Published: June 21, 2018

Hypertrophic Cardiomyopathy: A Vicious Cycle Triggered by Sarcomere Mutations and Secondary Disease Hits.

Hypertrophic Cardiomyopathy: A Vicious Cycle Triggered by Sarcomere Mutations and Secondary Disease Hits.

Journal: Antioxidants & redox signaling

Published: March 02, 2018

Contribution of Impaired Parasympathetic Activity to Right Ventricular Dysfunction and Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension.

Contribution of Impaired Parasympathetic Activity to Right Ventricular Dysfunction and Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension.

Journal: Circulation

Published: January 18, 2017

Comparison of the effects of a truncating and a missense MYBPC3 mutation on contractile parameters of engineered heart tissue.

Comparison of the effects of a truncating and a missense MYBPC3 mutation on contractile parameters of engineered heart tissue.

Journal: Journal of molecular and cellular cardiology

Published: December 18, 2015

ADP-stimulated contraction: A predictor of thin-filament activation in cardiac disease.

ADP-stimulated contraction: A predictor of thin-filament activation in cardiac disease.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: December 02, 2015

Showing 1-12 of 23

Last Updated: 09/26/2026