Paul M. Van Den Berk

Leiden, ZH, Netherlands

Last Updated: 09/26/2026

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Found 24 publications

Model-Informed Drug Development for Daprodustat Supports the Design of Individualized Dosing Regimens in Chronic Kidney Disease Patients With Anemia.

Model-Informed Drug Development for Daprodustat Supports the Design of Individualized Dosing Regimens in Chronic Kidney Disease Patients With Anemia.

Journal: Clinical pharmacology and therapeutics

Published: March 13, 2025

Integrated Longitudinal Population Dose-Hemoglobin Response of Daprodustat Following Dose Titration in Patients With Anemia in Chronic Kidney Disease.

Integrated Longitudinal Population Dose-Hemoglobin Response of Daprodustat Following Dose Titration in Patients With Anemia in Chronic Kidney Disease.

Journal: Clinical pharmacology and therapeutics

Published: June 19, 2024

Molecular dependencies and genomic consequences of a global DNA damage tolerance defect.

Molecular dependencies and genomic consequences of a global DNA damage tolerance defect.

Journal: Genome biology

Published: February 22, 2024

Pharmacokinetics and pharmacodynamics of finerenone in patients with chronic kidney disease and type 2 diabetes: Insights based on FIGARO-DKD and FIDELIO-DKD.

Pharmacokinetics and pharmacodynamics of finerenone in patients with chronic kidney disease and type 2 diabetes: Insights based on FIGARO-DKD and FIDELIO-DKD.

Journal: Diabetes, obesity & metabolism

Published: September 06, 2023

Hyoid bone morphology in patients with isolated robin sequence - A case-control study utilizing 3D morphable models.

Hyoid bone morphology in patients with isolated robin sequence - A case-control study utilizing 3D morphable models.

Journal: Bone reports

Published: September 04, 2023

Dual role of proliferating cell nuclear antigen monoubiquitination in facilitating Fanconi anemia-mediated interstrand crosslink repair.

Dual role of proliferating cell nuclear antigen monoubiquitination in facilitating Fanconi anemia-mediated interstrand crosslink repair.

Journal: PNAS nexus

Published: July 19, 2023

A C57BL/6J Fancg-KO Mouse Model Generated by CRISPR/Cas9 Partially Captures the Human Phenotype.

A C57BL/6J Fancg-KO Mouse Model Generated by CRISPR/Cas9 Partially Captures the Human Phenotype.

Journal: International journal of molecular sciences

Published: June 14, 2023

Mammalian life depends on two distinct pathways of DNA damage tolerance.

Mammalian life depends on two distinct pathways of DNA damage tolerance.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: January 20, 2023

Huwe1 supports B-cell development, B-cell-dependent immunity, somatic hypermutation and class switch recombination by regulating proliferation.

Huwe1 supports B-cell development, B-cell-dependent immunity, somatic hypermutation and class switch recombination by regulating proliferation.

Journal: Frontiers in immunology

Published: July 05, 2022

Division of labor within the DNA damage tolerance system reveals non-epistatic and clinically actionable targets for precision cancer medicine.

Division of labor within the DNA damage tolerance system reveals non-epistatic and clinically actionable targets for precision cancer medicine.

Journal: Nucleic acids research

Published: April 12, 2022

Green tooth discoloration in a two-year-old boy

Green tooth discoloration in a two-year-old boy

Journal: Nederlands tijdschrift voor tandheelkunde

Published: November 08, 2021

Finerenone Dose-Exposure-Response for the Primary Kidney Outcome in FIDELIO-DKD Phase III: Population Pharmacokinetic and Time-to-Event Analysis.

Finerenone Dose-Exposure-Response for the Primary Kidney Outcome in FIDELIO-DKD Phase III: Population Pharmacokinetic and Time-to-Event Analysis.

Journal: Clinical pharmacokinetics

Published: October 08, 2021

Showing 1-12 of 24

Last Updated: 09/26/2026