Paul P. Geurink

Leiden, ZH, Netherlands

Last Updated: 09/26/2026

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Found 50 publications

USP8 controls proteostasis pathways in B cells and multiple myeloma.

USP8 controls proteostasis pathways in B cells and multiple myeloma.

Journal: Leukemia

Published: April 09, 2026

Pharmacological inhibition of USP18 improves antibacterial responses and the intracellular control of Mycobacterium tuberculosis in macrophages.

Pharmacological inhibition of USP18 improves antibacterial responses and the intracellular control of Mycobacterium tuberculosis in macrophages.

Journal: Frontiers in immunology

Published: November 04, 2025

Development and Validation of a High-Throughput Screening Assay for the Legionella ADP-Ribosyl Transferase SdeA.

Development and Validation of a High-Throughput Screening Assay for the Legionella ADP-Ribosyl Transferase SdeA.

Journal: Chembiochem : a European journal of chemical biology

Published: July 04, 2025

High-Throughput Synthesis and Screening of a Cyanimide Library Identifies Selective Inhibitors of ISG15-Specific Protease mUSP18.

High-Throughput Synthesis and Screening of a Cyanimide Library Identifies Selective Inhibitors of ISG15-Specific Protease mUSP18.

Journal: Angewandte Chemie (International ed. in English)

Published: May 19, 2025

A drug-repurposing screen of FDA- and EMA-approved drugs identifies two NF-κB inhibitors active against eumycetoma.

A drug-repurposing screen of FDA- and EMA-approved drugs identifies two NF-κB inhibitors active against eumycetoma.

Journal: The Journal of antimicrobial chemotherapy

Published: May 18, 2025

USP24 is a cross-reactive DUB targeting MOV10 to regulate IFN-I production.

USP24 is a cross-reactive DUB targeting MOV10 to regulate IFN-I production.

Journal: Nature communications

Published: September 30, 2024

A functional screen for ubiquitin regulation identifies an E3 ligase secreted by Pseudomonas aeruginosa.

A functional screen for ubiquitin regulation identifies an E3 ligase secreted by Pseudomonas aeruginosa.

Journal: bioRxiv : the preprint server for biology

Published: September 30, 2024

Development of Inhibitors, Probes, and PROTAC Provides a Complete Toolbox to Study PARK7 in the Living Cell.

Development of Inhibitors, Probes, and PROTAC Provides a Complete Toolbox to Study PARK7 in the Living Cell.

Journal: Journal of medicinal chemistry

Published: May 07, 2024

High-throughput competitive binding assay for targeting RNA tertiary structures with small molecules: application to pseudoknots and G-quadruplexes.

High-throughput competitive binding assay for targeting RNA tertiary structures with small molecules: application to pseudoknots and G-quadruplexes.

Journal: Nucleic acids research

Published: April 18, 2024

Bacterial esterases reverse lipopolysaccharide ubiquitylation to block host immunity.

Bacterial esterases reverse lipopolysaccharide ubiquitylation to block host immunity.

Journal: Cell host & microbe

Published: February 14, 2024

Deubiquitinating activity of SARS-CoV-2 papain-like protease does not influence virus replication or innate immune responses in vivo.

Deubiquitinating activity of SARS-CoV-2 papain-like protease does not influence virus replication or innate immune responses in vivo.

Journal: PLoS pathogens

Published: January 19, 2024

USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism.

USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: December 06, 2023

Showing 1-12 of 50

Last Updated: 09/26/2026