Paul Saftig

Kiel, SH, Germany

Last Updated: 09/26/2026

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Found 156 publications

LIMP-2 deficiency-associated glycolipid abnormalities in mice.

LIMP-2 deficiency-associated glycolipid abnormalities in mice.

Journal: Biochimica et biophysica acta. Molecular and cell biology of lipids

Published: April 08, 2025

Autoantibody-triggered podocyte membrane budding drives autoimmune kidney disease.

Autoantibody-triggered podocyte membrane budding drives autoimmune kidney disease.

Journal: Cell

Published: March 18, 2025

Correction: Potential role for Cathepsin D in p53-dependent tumor suppression and chemosensitivity.

Correction: Potential role for Cathepsin D in p53-dependent tumor suppression and chemosensitivity.

Journal: Oncogene

Published: February 11, 2025

Leveraging the ADAM10 prodomain for selective inhibition to enhance recovery after myocardial infarction.

Leveraging the ADAM10 prodomain for selective inhibition to enhance recovery after myocardial infarction.

Journal: British journal of pharmacology

Published: November 28, 2024

Regulation of podocyte surface proteins by the enzyme A Disintegrin And Metalloproteinase 10 (ADAM10).

Regulation of podocyte surface proteins by the enzyme A Disintegrin And Metalloproteinase 10 (ADAM10).

Journal: Kidney international

Published: August 20, 2024

Inhibition of BACE1 affected both its Aβ producing and degrading activities and increased Aβ42 and Aβ40 levels at high-level BACE1 expression.

Inhibition of BACE1 affected both its Aβ producing and degrading activities and increased Aβ42 and Aβ40 levels at high-level BACE1 expression.

Journal: The Journal of biological chemistry

Published: February 28, 2024

Recombinant cathepsins B and L promote α-synuclein clearance and restore lysosomal function in human and murine models with α-synuclein pathology.

Recombinant cathepsins B and L promote α-synuclein clearance and restore lysosomal function in human and murine models with α-synuclein pathology.

Journal: Molecular neurodegeneration

Published: February 22, 2024

Non-canonical function of ADAM10 in presynaptic plasticity.

Non-canonical function of ADAM10 in presynaptic plasticity.

Journal: Cellular and molecular life sciences : CMLS

Published: February 20, 2024

TIMP1 Mediates Astrocyte-Dependent Local Immunosuppression in Brain Metastasis Acting on Infiltrating CD8+ T Cells.

TIMP1 Mediates Astrocyte-Dependent Local Immunosuppression in Brain Metastasis Acting on Infiltrating CD8+ T Cells.

Journal: Cancer discovery

Published: January 31, 2024

Cellular depletion of major cathepsin proteases reveals their concerted activities for lysosomal proteolysis.

Cellular depletion of major cathepsin proteases reveals their concerted activities for lysosomal proteolysis.

Journal: Cellular and molecular life sciences : CMLS

Published: January 24, 2024

MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes.

MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes.

Journal: Nature cell biology

Published: January 22, 2024

Sphingosine-1-phosphate signalling activates E-Syt1 to facilitate HDL-derived cholesterol transport.

Sphingosine-1-phosphate signalling activates E-Syt1 to facilitate HDL-derived cholesterol transport.

Journal: Nature cell biology

Published: January 14, 2024

Showing 1-12 of 156

Last Updated: 09/26/2026