Paul Van Slyke

661 University Ave #465
Toronto, ON M5G1M1, Canada

Last Updated: 09/26/2026

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Found 16 publications

Adjunctive therapy with the Tie2 agonist Vasculotide reduces pulmonary permeability in Streptococcus pneumoniae infected and mechanically ventilated mice.

Adjunctive therapy with the Tie2 agonist Vasculotide reduces pulmonary permeability in Streptococcus pneumoniae infected and mechanically ventilated mice.

Journal: Scientific reports

Published: December 08, 2021

The effect of targeting Tie2 on hemorrhagic shock-induced renal perfusion disturbances in rats.

The effect of targeting Tie2 on hemorrhagic shock-induced renal perfusion disturbances in rats.

Journal: Intensive care medicine experimental

Published: February 23, 2021

Vasculotide restores the blood-brain barrier after focused ultrasound-induced permeability in a mouse model of Alzheimer's disease.

Vasculotide restores the blood-brain barrier after focused ultrasound-induced permeability in a mouse model of Alzheimer's disease.

Journal: International journal of medical sciences

Published: June 12, 2020

Erratum: Tie2 Activation Promotes Protection and Reconstitution of the Endothelial Glycocalyx in Human Sepsis.

Erratum: Tie2 Activation Promotes Protection and Reconstitution of the Endothelial Glycocalyx in Human Sepsis.

Journal: Thrombosis and haemostasis

Published: January 30, 2020

Tie2 Activation Promotes Protection and Reconstitution of the Endothelial Glycocalyx in Human Sepsis.

Tie2 Activation Promotes Protection and Reconstitution of the Endothelial Glycocalyx in Human Sepsis.

Journal: Thrombosis and haemostasis

Published: September 08, 2019

Angiopoietin-1 Mimetic Peptide Promotes Neuroprotection after Stroke in Type 1 Diabetic Rats.

Angiopoietin-1 Mimetic Peptide Promotes Neuroprotection after Stroke in Type 1 Diabetic Rats.

Journal: Cell transplantation

Published: August 21, 2018

Tie2 signalling through Erk1/2 regulates TLR4 driven inflammation.

Tie2 signalling through Erk1/2 regulates TLR4 driven inflammation.

Journal: Cellular signalling

Published: June 15, 2018

Vasculotide, an angiopoietin-1 mimetic, reduces pulmonary vascular leakage and preserves microcirculatory perfusion during cardiopulmonary bypass in rats.

Vasculotide, an angiopoietin-1 mimetic, reduces pulmonary vascular leakage and preserves microcirculatory perfusion during cardiopulmonary bypass in rats.

Journal: British journal of anaesthesia

Published: December 08, 2017

Vasculotide, an Angiopoietin-1 Mimetic, Restores Microcirculatory Perfusion and Microvascular Leakage and Decreases Fluid Resuscitation Requirements in Hemorrhagic Shock.

Vasculotide, an Angiopoietin-1 Mimetic, Restores Microcirculatory Perfusion and Microvascular Leakage and Decreases Fluid Resuscitation Requirements in Hemorrhagic Shock.

Journal: Anesthesiology

Published: October 03, 2017

Vasculotide reduces pulmonary hyperpermeability in experimental pneumococcal pneumonia.

Vasculotide reduces pulmonary hyperpermeability in experimental pneumococcal pneumonia.

Journal: Critical care (London, England)

Published: July 06, 2017

Pharmacological Tie2 activation in kidney transplantation.

Pharmacological Tie2 activation in kidney transplantation.

Journal: World journal of transplantation

Published: March 30, 2016

The Synthetic Tie2 Agonist Peptide Vasculotide Protects Renal Vascular Barrier Function In Experimental Acute Kidney Injury.

The Synthetic Tie2 Agonist Peptide Vasculotide Protects Renal Vascular Barrier Function In Experimental Acute Kidney Injury.

Journal: Scientific reports

Published: September 28, 2015

Showing 1-12 of 16

Last Updated: 09/26/2026