Paul W. Smith

10 Biopolis Road, Chromos #05-01
Singapore, 138670, Singapore

Last Updated: 09/26/2026

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Found 19 publications

Benzoheterocyclic Oxime Carbamates Active against Mycobacterium tuberculosis: Synthesis, Structure-Activity Relationship, Metabolism, and Biology Triaging.

Benzoheterocyclic Oxime Carbamates Active against Mycobacterium tuberculosis: Synthesis, Structure-Activity Relationship, Metabolism, and Biology Triaging.

Journal: Journal of medicinal chemistry

Published: June 17, 2021

Pharmacokinetics of β-Lactam Antibiotics: Clues from the Past To Help Discover Long-Acting Oral Drugs in the Future.

Pharmacokinetics of β-Lactam Antibiotics: Clues from the Past To Help Discover Long-Acting Oral Drugs in the Future.

Journal: ACS infectious diseases

Published: August 25, 2018

Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design.

Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design.

Journal: Journal of medicinal chemistry

Published: March 18, 2016

A Conserved Pocket in the Dengue Virus Polymerase Identified through Fragment-based Screening.

A Conserved Pocket in the Dengue Virus Polymerase Identified through Fragment-based Screening.

Journal: The Journal of biological chemistry

Published: January 04, 2016

Pyrrolo[3,4-c]pyridine-1,3(2H)-diones: A Novel Antimycobacterial Class Targeting Mycobacterial Respiration.

Pyrrolo[3,4-c]pyridine-1,3(2H)-diones: A Novel Antimycobacterial Class Targeting Mycobacterial Respiration.

Journal: Journal of medicinal chemistry

Published: November 10, 2015

Artificial Neural Network Analysis of Pharmacokinetic and Toxicity Properties of Lead Molecules for Dengue Fever, Tuberculosis and Malaria.

Artificial Neural Network Analysis of Pharmacokinetic and Toxicity Properties of Lead Molecules for Dengue Fever, Tuberculosis and Malaria.

Journal: Current computer-aided drug design

Published: July 07, 2015

Structure activity relationships of 4-hydroxy-2-pyridones: A novel class of antituberculosis agents.

Structure activity relationships of 4-hydroxy-2-pyridones: A novel class of antituberculosis agents.

Journal: European journal of medicinal chemistry

Published: June 15, 2015

Discovery of Dengue Virus NS4B Inhibitors.

Discovery of Dengue Virus NS4B Inhibitors.

Journal: Journal of virology

Published: May 29, 2015

Direct inhibitors of InhA are active against Mycobacterium tuberculosis.

Direct inhibitors of InhA are active against Mycobacterium tuberculosis.

Journal: Science translational medicine

Published: January 09, 2015

Therapeutics for Neglected Infectious Diseases: Progress and Challenge.

Therapeutics for Neglected Infectious Diseases: Progress and Challenge.

Journal: ACS infectious diseases

Published: January 09, 2015

Lead optimization of spiropyrazolopyridones: a new and potent class of dengue virus inhibitors.

Lead optimization of spiropyrazolopyridones: a new and potent class of dengue virus inhibitors.

Journal: ACS medicinal chemistry letters

Published: December 16, 2014

Perspective: Challenges and opportunities in TB drug discovery from phenotypic screening.

Perspective: Challenges and opportunities in TB drug discovery from phenotypic screening.

Journal: Bioorganic & medicinal chemistry

Published: October 29, 2014

Showing 1-12 of 19

Last Updated: 09/26/2026