Paulynn S. Chin

Birmingham, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 19 publications

CD248/Endosialin regulates synovial fibroblast state to control coupling of inflammation and bone damage in murine models of immune-mediated inflammatory arthritis and ageing.

CD248/Endosialin regulates synovial fibroblast state to control coupling of inflammation and bone damage in murine models of immune-mediated inflammatory arthritis and ageing.

Journal: Arthritis & rheumatology (Hoboken, N.J.)
Published: December 02, 2025

Synovial tissue atlas in juvenile idiopathic arthritis reveals pathogenic niches associated with disease severity.

Synovial tissue atlas in juvenile idiopathic arthritis reveals pathogenic niches associated with disease severity.

Journal: Science translational medicine
Published: July 02, 2025

Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1.

Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1.

Journal: iScience
Published: October 23, 2023

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.

Journal: bioRxiv : the preprint server for biology
Published: July 28, 2023

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.

Journal: Cell reports
Published: July 13, 2023

Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth.

Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth.

Journal: Nature communications
Published: May 02, 2023

Identification and interrogation of the gene regulatory network of CEBPA-double mutant acute myeloid leukemia.

Identification and interrogation of the gene regulatory network of CEBPA-double mutant acute myeloid leukemia.

Journal: Leukemia
Published: June 17, 2022

Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia.

Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia.

Journal: Blood
Published: December 03, 2021

t(8;21) Acute Myeloid Leukemia as a Paradigm for the Understanding of Leukemogenesis at the Level of Gene Regulation and Chromatin Programming.

t(8;21) Acute Myeloid Leukemia as a Paradigm for the Understanding of Leukemogenesis at the Level of Gene Regulation and Chromatin Programming.

Journal: Cells
Published: November 23, 2020

RUNX1/ETO and mutant KIT both contribute to programming the transcriptional and chromatin landscape in t(8;21) acute myeloid leukemia.

RUNX1/ETO and mutant KIT both contribute to programming the transcriptional and chromatin landscape in t(8;21) acute myeloid leukemia.

Journal: Experimental hematology
Published: October 26, 2020

Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1.

Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1.

Journal: Cell reports
Published: August 07, 2020

Modelling t(8;21) acute myeloid leukaemia - What have we learned?

Modelling t(8;21) acute myeloid leukaemia - What have we learned?

Journal: MedComm
Published: July 07, 2020
Showing 1-12 of 19

Last Updated: 09/26/2026