Pavan Vajjah
Biopharmaceuticals R&D, AstraZeneca
Cambridge, ENG, United Kingdom
Cambridge, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 12 publications
Learnings from Approved Antibody-Drug Conjugates: Clinical Pharmacology Perspectives.
Journal: Journal of clinical pharmacology
Published: September 26, 2025
Exposure-Response Analyses of Datopotamab Deruxtecan (Dato-DXd) in Patients with Hormone Receptor (HR) Positive, Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Breast Cancer.
Journal: Journal of clinical pharmacology
Published: September 22, 2025
Optimal Dosage Justification for Datopotamab Deruxtecan in HR-Positive/HER2-Negative Breast Cancer Through Model-Informed Drug Development Approaches.
Journal: Clinical and translational science
Published: July 24, 2025
Strategies for clinical dose optimization of T cell-engaging therapies in oncology.
Journal: mAbs
Published: February 23, 2023
Population Pharmacokinetics and Exposure-Response for Dapirolizumab Pegol From a Phase 2b Trial in Patients With Systemic Lupus Erythematosus.
Journal: Journal of clinical pharmacology
Published: June 23, 2022
Bimekizumab for the treatment of moderate-to-severe plaque psoriasis: efficacy, safety, pharmacokinetics, pharmacodynamics and transcriptomics from a phase IIa, randomized, double-blind multicentre study.
Journal: The British journal of dermatology
Published: October 19, 2021
Bimekizumab, a Novel Humanized IgG1 Antibody That Neutralizes Both IL-17A and IL-17F.
Journal: Frontiers in immunology
Published: December 13, 2019
Dual IL-17A and IL-17F neutralisation by bimekizumab in psoriatic arthritis: evidence from preclinical experiments and a randomised placebo-controlled clinical trial that IL-17F contributes to human chronic tissue inflammation.
Journal: Annals of the rheumatic diseases
Published: July 26, 2017
First-in-human randomized study of bimekizumab, a humanized monoclonal antibody and selective dual inhibitor of IL-17A and IL-17F, in mild psoriasis.
Journal: British journal of clinical pharmacology
Published: June 22, 2016
Does age affect gastric emptying time? A model-based meta-analysis of data from premature neonates through to adults.
Journal: Biopharmaceutics & drug disposition
Published: October 17, 2014
Precision criteria to derive sample size when designing pediatric pharmacokinetic studies: which measure of variability should be used?
Journal: Journal of clinical pharmacology
Published: July 18, 2013
Showing 1-12 of 12
Last Updated: 09/26/2026