Pavel Kielkowski

Munich, BY, Germany

Last Updated: 09/26/2026

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Found 34 publications

Aberrant FICD-mediated AMPylation drives α-Synuclein pathology and overall protein dyshomeostasis in dopaminergic neurons in Parkinson's disease.

Aberrant FICD-mediated AMPylation drives α-Synuclein pathology and overall protein dyshomeostasis in dopaminergic neurons in Parkinson's disease.

Journal: bioRxiv : the preprint server for biology

Published: April 10, 2026

Lysosomal channel TPC2 modulates microglia-endothelial signaling in choroidal angiogenesis.

Lysosomal channel TPC2 modulates microglia-endothelial signaling in choroidal angiogenesis.

Journal: Angiogenesis

Published: March 18, 2026

Csf1r-mediated depletion of myeloid cells prevents dopaminergic neuron loss during chronic colitis.

Csf1r-mediated depletion of myeloid cells prevents dopaminergic neuron loss during chronic colitis.

Journal: Journal of neuroinflammation

Published: February 26, 2026

A cysteine reactive chloroalkane probe enables HaloTag ligation for downstream chemical proteomics analysis.

A cysteine reactive chloroalkane probe enables HaloTag ligation for downstream chemical proteomics analysis.

Journal: RSC chemical biology

Published: January 08, 2026

AdiY acts as a cytoplasmic pH sensor via histidine protonation to regulate acid stress adaptation in Escherichia coli.

AdiY acts as a cytoplasmic pH sensor via histidine protonation to regulate acid stress adaptation in Escherichia coli.

Journal: Journal of bacteriology

Published: December 23, 2025

Expression, purification and functional validation of a cancer-associated isoform of the HBx protein from human hepatitis B virus.

Expression, purification and functional validation of a cancer-associated isoform of the HBx protein from human hepatitis B virus.

Journal: Protein expression and purification

Published: September 23, 2025

Horizontal transfer of post-translational modifiers brings evolutionary opportunity and challenges to a conserved translation factor.

Horizontal transfer of post-translational modifiers brings evolutionary opportunity and challenges to a conserved translation factor.

Journal: BMC biology

Published: August 14, 2025

Targeting the Spliceosomal Protein USP39 Through Allosteric Ligands and PROTAC-Induced Degradation.

Targeting the Spliceosomal Protein USP39 Through Allosteric Ligands and PROTAC-Induced Degradation.

Journal: Angewandte Chemie (International ed. in English)

Published: July 31, 2025

Vimentin network dysregulation mediates neurite deficits in SNCA duplication Parkinson's patient-derived midbrain neurons.

Vimentin network dysregulation mediates neurite deficits in SNCA duplication Parkinson's patient-derived midbrain neurons.

Journal: Science advances

Published: June 06, 2025

A Highly Reactive Cysteine-Targeted Acrylophenone Chemical Probe That Enables Peptide/Protein Bioconjugation and Chemoproteomics Analysis.

A Highly Reactive Cysteine-Targeted Acrylophenone Chemical Probe That Enables Peptide/Protein Bioconjugation and Chemoproteomics Analysis.

Journal: JACS Au

Published: June 03, 2025

Self-assembled PROTACs enable glycoproteins degradation in the living cells.

Self-assembled PROTACs enable glycoproteins degradation in the living cells.

Journal: Chemical science

Published: January 16, 2025

AMPylation Regulates 5'-3' Exonuclease PLD3 Processing.

AMPylation Regulates 5'-3' Exonuclease PLD3 Processing.

Journal: Molecular & cellular proteomics : MCP

Published: November 12, 2024

Showing 1-12 of 34

Last Updated: 09/26/2026