Pavel Mares

Prague, PR, Czech Republic

Last Updated: 09/26/2026

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Found 86 publications

Pregnanolone-Based Prodrugs as a Strategy for Neuroprotective Drug-Like Compounds: Pregnanolone Pyroglutamate and Its Age‑dependent Anticonvulsant Effects in the 6-hz Seizure Model in Immature Rats.

Pregnanolone-Based Prodrugs as a Strategy for Neuroprotective Drug-Like Compounds: Pregnanolone Pyroglutamate and Its Age‑dependent Anticonvulsant Effects in the 6-hz Seizure Model in Immature Rats.

Journal: Drug design, development and therapy

Published: November 12, 2025

NMDA receptors play an important role in postictal potentiation in immature rats.

NMDA receptors play an important role in postictal potentiation in immature rats.

Journal: Frontiers in synaptic neuroscience

Published: November 08, 2025

Early life exposure to clonazepam has both short- and long-term effects on seizures induced with pentylenetetrazol (PTZ).

Early life exposure to clonazepam has both short- and long-term effects on seizures induced with pentylenetetrazol (PTZ).

Journal: Frontiers in pharmacology

Published: October 15, 2025

Seizures elicited by transcorneal 6 Hz stimulation in developing rats.

Seizures elicited by transcorneal 6 Hz stimulation in developing rats.

Journal: PloS one

Published: May 20, 2024

Epilepsy Research in the Institute of Physiology of the Czech Academy of Sciences in Prague.

Epilepsy Research in the Institute of Physiology of the Czech Academy of Sciences in Prague.

Journal: Physiological research

Published: May 16, 2024

Degenerative Changes in the Claustrum and Endopiriform Nucleus after Early-Life Status Epilepticus in Rats.

Degenerative Changes in the Claustrum and Endopiriform Nucleus after Early-Life Status Epilepticus in Rats.

Journal: International journal of molecular sciences

Published: November 13, 2023

Adenosine A1 Receptors Participate in Excitability Changes after Cortical Epileptic Afterdischarges in Immature Rats.

Adenosine A1 Receptors Participate in Excitability Changes after Cortical Epileptic Afterdischarges in Immature Rats.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: September 30, 2023

The outcome of early life status epilepticus-lessons from laboratory animals.

The outcome of early life status epilepticus-lessons from laboratory animals.

Journal: Epilepsia open

Published: June 18, 2022

Adenosine Kinase Isoforms in the Developing Rat Hippocampus after LiCl/Pilocarpine Status Epilepticus.

Adenosine Kinase Isoforms in the Developing Rat Hippocampus after LiCl/Pilocarpine Status Epilepticus.

Journal: International journal of molecular sciences

Published: January 30, 2022

The Neuroactive Steroid Pregnanolone Glutamate: Anticonvulsant Effect, Metabolites and Its Effect on Neurosteroid Levels in Developing Rat Brains.

The Neuroactive Steroid Pregnanolone Glutamate: Anticonvulsant Effect, Metabolites and Its Effect on Neurosteroid Levels in Developing Rat Brains.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: November 30, 2021

Anticonvulsive Effects and Pharmacokinetic Profile of Cannabidiol (CBD) in the Pentylenetetrazol (PTZ) or N-Methyl-D-Aspartate (NMDA) Models of Seizures in Infantile Rats.

Anticonvulsive Effects and Pharmacokinetic Profile of Cannabidiol (CBD) in the Pentylenetetrazol (PTZ) or N-Methyl-D-Aspartate (NMDA) Models of Seizures in Infantile Rats.

Journal: International journal of molecular sciences

Published: November 25, 2021

The GluN2B-Selective Antagonist Ro 25-6981 Is Effective against PTZ-Induced Seizures and Safe for Further Development in Infantile Rats.

The GluN2B-Selective Antagonist Ro 25-6981 Is Effective against PTZ-Induced Seizures and Safe for Further Development in Infantile Rats.

Journal: Pharmaceutics

Published: August 14, 2021

Showing 1-12 of 86

Last Updated: 09/26/2026