Pawel Lis

Dow Street
Dundee, SCT DD15EH, United Kingdom

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 37 publications

Large-scale functional annotation establishes a reference framework for human LRRK2 variants.

Large-scale functional annotation establishes a reference framework for human LRRK2 variants.

Journal: medRxiv : the preprint server for health sciences

Published: July 03, 2026

NRBP1 pseudokinase binds to and activates the WNK pathway in response to osmotic stress.

NRBP1 pseudokinase binds to and activates the WNK pathway in response to osmotic stress.

Journal: Science advances

Published: July 16, 2025

Functional and Structural Characterization of LRRK2 p.V1447L in Parkinson's Disease.

Functional and Structural Characterization of LRRK2 p.V1447L in Parkinson's Disease.

Journal: Movement disorders : official journal of the Movement Disorder Society

Published: April 22, 2025

Endogenous LRRK2 and PINK1 function in a convergent neuroprotective ciliogenesis pathway in the brain.

Endogenous LRRK2 and PINK1 function in a convergent neuroprotective ciliogenesis pathway in the brain.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: January 28, 2025

Variants in the proteasome regulator PSMF1 cause a phenotypic spectrum from early-onset Parkinson's disease to perinatal lethality and disrupt mitochondrial function.

Variants in the proteasome regulator PSMF1 cause a phenotypic spectrum from early-onset Parkinson's disease to perinatal lethality and disrupt mitochondrial function.

Journal: medRxiv : the preprint server for health sciences

Published: August 16, 2024

Clinical and functional evidence for the pathogenicity of the LRRK2 p.Arg1067Gln variant.

Clinical and functional evidence for the pathogenicity of the LRRK2 p.Arg1067Gln variant.

Journal: NPJ Parkinson's disease

Published: August 15, 2024

Variants in the proteasome regulator PSMF1 cause a phenotypic spectrum from parkinsonism to perinatal lethality.

Variants in the proteasome regulator PSMF1 cause a phenotypic spectrum from parkinsonism to perinatal lethality.

Journal: Nature communications

Published: July 14, 2024

Tagless LysoIP for immunoaffinity enrichment of native lysosomes from clinical samples.

Tagless LysoIP for immunoaffinity enrichment of native lysosomes from clinical samples.

Journal: The Journal of clinical investigation

Published: July 01, 2024

A pathogenic variant in RAB32 causes autosomal dominant Parkinson's disease and activates LRRK2 kinase.

A pathogenic variant in RAB32 causes autosomal dominant Parkinson's disease and activates LRRK2 kinase.

Journal: medRxiv : the preprint server for health sciences

Published: January 31, 2024

RAB32 Ser71Arg in autosomal dominant Parkinson's disease: linkage, association, and functional analyses.

RAB32 Ser71Arg in autosomal dominant Parkinson's disease: linkage, association, and functional analyses.

Journal: The Lancet. Neurology

Published: January 05, 2024

Parkinson's VPS35[D620N] mutation induces LRRK2-mediated lysosomal association of RILPL1 and TMEM55B.

Parkinson's VPS35[D620N] mutation induces LRRK2-mediated lysosomal association of RILPL1 and TMEM55B.

Journal: Science advances

Published: December 13, 2023

Endogenous Rab38 regulates LRRK2's membrane recruitment and substrate Rab phosphorylation in melanocytes.

Endogenous Rab38 regulates LRRK2's membrane recruitment and substrate Rab phosphorylation in melanocytes.

Journal: The Journal of biological chemistry

Published: May 26, 2023

Showing 1-12 of 37

Last Updated: 09/26/2026