Peng Chu
Lvshun South Street
Dalian, 116044, China
Dalian, 116044, China
Last Updated: 09/26/2026
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Found 53 publications
Design and Synthesis of KRASG12C Inhibitors for Antitumor Evaluation Harboring Combination Therapy with Nrf2, PARP-7, and Pan-USP Inhibitors to Alleviate Drug Resistance Synergistically.
Journal: Journal of medicinal chemistry
Published: February 03, 2026
Covalent JAK3 inhibitors based on 2-arylamino and 7H-pyrrolo[2,3-d]pyrimidine scaffold: design, synthesis, and biological evaluation for the potential treatment of bortezomib-resistant multiple myeloma.
Journal: European journal of medicinal chemistry
Published: January 04, 2026
Integrated network pharmacology and experimental models uncover the mechanism of procyanidin B2 against ovarian carcinoma via EGFR/AKT pathway.
Journal: Biochemical and biophysical research communications
Published: November 27, 2025
Isoginkgetin as a novel USP8 inhibitor discovered by structure-based virtual screening exerts anticancer effects in ovarian cancer.
Journal: Biochemical and biophysical research communications
Published: October 29, 2025
SIRT2-mediated deacetylation activates USP22 catalytic function for PD-L1 protein stabilization and tumor immune escape.
Journal: The Journal of clinical investigation
Published: July 22, 2025
Spotlight on USP30: structure, function, disease and target inhibition.
Journal: Frontiers in pharmacology
Published: May 16, 2025
Corrigendum "Enhancement of gemcitabine efficacy by K73-03 via epigenetically regulation of miR-421/SPINK1 in gemcitabine resistant pancreatic cancer cells" [Phytomedicine 2021:91:153711].
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology
Published: December 13, 2024
Discovery of Baicalein as a Novel Ubiquitin-Specific Protease 21 Inhibitor for the Treatment of Hepatocellular Carcinoma.
Journal: Phytotherapy research : PTR
Published: December 02, 2024
Phosphocreatine ameliorates hepatocellular apoptosis mediated by protecting mitochondrial damage in liver ischemia/reperfusion injury through inhibiting TLR4 and Agonizing Akt Pathway.
Journal: Tissue & cell
Published: September 16, 2024
The secoiridoid glycoside Gentiopicroside is a USP22 inhibitor with potent antitumor immunotherapeutic activity.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: March 29, 2024
Hepatocyte growth factor promotes melanoma metastasis through ubiquitin-specific peptidase 22-mediated integrins upregulation.
Journal: Cancer letters
Published: January 22, 2024
Last Updated: 09/26/2026