Peng Yin

Guangzhou, China

Last Updated: 09/26/2026

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Found 46 publications

Caspase-4 transgenic mice exhibit cytoplasmic TDP-43 accumulation and age-dependent neuropathology.

Caspase-4 transgenic mice exhibit cytoplasmic TDP-43 accumulation and age-dependent neuropathology.

Journal: Nature communications
Published: January 23, 2026

Inhibition of UBE2N promotes the clearance of mutant HTT (huntingtin) in HD knock-in mice.

Inhibition of UBE2N promotes the clearance of mutant HTT (huntingtin) in HD knock-in mice.

Journal: Autophagy
Published: August 16, 2025

Precise excision of expanded GGC repeats in NOTCH2NLC via CRISPR/Cas9 for treating neuronal intranuclear inclusion disease.

Precise excision of expanded GGC repeats in NOTCH2NLC via CRISPR/Cas9 for treating neuronal intranuclear inclusion disease.

Journal: Nature communications
Published: May 15, 2025

Ribosome-associated pathological TDP-43 alters the expression of multiple mRNAs in the monkey brain.

Ribosome-associated pathological TDP-43 alters the expression of multiple mRNAs in the monkey brain.

Journal: Zoological research
Published: February 20, 2025

Multimodal brain cell atlas across the adult macaque lifespan.

Multimodal brain cell atlas across the adult macaque lifespan.

Journal: Cell
Published: January 03, 2025

Increased expression of mesencephalic astrocyte-derived neurotrophic factor (MANF) contributes to synapse loss in Alzheimer's disease.

Increased expression of mesencephalic astrocyte-derived neurotrophic factor (MANF) contributes to synapse loss in Alzheimer's disease.

Journal: Molecular neurodegeneration
Published: September 09, 2024

Application of antisense oligonucleotide drugs in amyotrophic lateral sclerosis and Huntington's disease.

Application of antisense oligonucleotide drugs in amyotrophic lateral sclerosis and Huntington's disease.

Journal: Translational neurodegeneration
Published: June 11, 2024

TRIM37 is a primate-specific E3 ligase for Huntingtin and accounts for the striatal degeneration in Huntington's disease.

TRIM37 is a primate-specific E3 ligase for Huntingtin and accounts for the striatal degeneration in Huntington's disease.

Journal: Science advances
Published: May 17, 2024

Pathogenic TDP-43 accelerates the generation of toxic exon1 HTT in Huntington's disease knock-in mice.

Pathogenic TDP-43 accelerates the generation of toxic exon1 HTT in Huntington's disease knock-in mice.

Journal: Aging cell
Published: April 03, 2024

Suppressing UBE2N ameliorates Alzheimer's disease pathology through the clearance of amyloid beta.

Suppressing UBE2N ameliorates Alzheimer's disease pathology through the clearance of amyloid beta.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association
Published: March 13, 2024

Deficiency of parkin causes neurodegeneration and accumulation of pathological α-synuclein in monkey models.

Deficiency of parkin causes neurodegeneration and accumulation of pathological α-synuclein in monkey models.

Journal: The Journal of clinical investigation
Published: January 22, 2024

Mutant THAP11 causes cerebellar neurodegeneration and triggers TREM2-mediated microglial activation in mice.

Mutant THAP11 causes cerebellar neurodegeneration and triggers TREM2-mediated microglial activation in mice.

Journal: The Journal of clinical investigation
Published: December 08, 2023
Showing 1-12 of 46

Last Updated: 09/26/2026