Peter E. Light

Edmonton, AB, Canada

Last Updated: 09/26/2026

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Found 59 publications

Residue-level insights into SGLT2 inhibition and Nav1.5 selectivity of gliflozin derivatives: A molecular dynamics and pharmacophore-guided study.

Residue-level insights into SGLT2 inhibition and Nav1.5 selectivity of gliflozin derivatives: A molecular dynamics and pharmacophore-guided study.

Journal: Journal of molecular graphics & modelling

Published: May 20, 2026

Late INa as a Therapeutic Target: New Strategies, Computational Modelling, Drug Development, and Clinical Translation.

Late INa as a Therapeutic Target: New Strategies, Computational Modelling, Drug Development, and Clinical Translation.

Journal: Medicinal research reviews

Published: November 17, 2025

Multiscale computational analysis reveals enhanced allosteric modulation of Nav1.5 by dual binding of dapagliflozin and ertugliflozin.

Multiscale computational analysis reveals enhanced allosteric modulation of Nav1.5 by dual binding of dapagliflozin and ertugliflozin.

Journal: Scientific reports

Published: September 12, 2025

Furin may contribute to proglucagon processing and glucagon-like Peptide-1 production in human alpha cells.

Furin may contribute to proglucagon processing and glucagon-like Peptide-1 production in human alpha cells.

Journal: Molecular metabolism

Published: July 11, 2025

The sodium/glucose cotransporter 2 inhibitor Empagliflozin inhibits long QT 3 late sodium currents in a mutation specific manner.

The sodium/glucose cotransporter 2 inhibitor Empagliflozin inhibits long QT 3 late sodium currents in a mutation specific manner.

Journal: Journal of molecular and cellular cardiology

Published: June 28, 2024

Glyburide use is associated with a greater likelihood of mortality or rehospitalization after acute coronary syndrome compared to gliclazide use in adults with type 2 diabetes: A cohort study.

Glyburide use is associated with a greater likelihood of mortality or rehospitalization after acute coronary syndrome compared to gliclazide use in adults with type 2 diabetes: A cohort study.

Journal: Diabetes, obesity & metabolism

Published: May 02, 2024

In-human testing of a non-invasive continuous low-energy microwave glucose sensor with advanced machine learning capabilities.

In-human testing of a non-invasive continuous low-energy microwave glucose sensor with advanced machine learning capabilities.

Journal: Biosensors & bioelectronics

Published: April 02, 2023

Regulation of PKD2 channel function by TACAN.

Regulation of PKD2 channel function by TACAN.

Journal: The Journal of physiology

Published: November 01, 2022

Non-Invasive Lactate Monitoring System Using Wearable Chipless Microwave Sensors With Enhanced Sensitivity and Zero Power Consumption.

Non-Invasive Lactate Monitoring System Using Wearable Chipless Microwave Sensors With Enhanced Sensitivity and Zero Power Consumption.

Journal: IEEE transactions on bio-medical engineering

Published: March 25, 2022

Cardiac mechanisms of the beneficial effects of SGLT2 inhibitors in heart failure: Evidence for potential off-target effects.

Cardiac mechanisms of the beneficial effects of SGLT2 inhibitors in heart failure: Evidence for potential off-target effects.

Journal: Journal of molecular and cellular cardiology

Published: January 24, 2022

Mixed SYGnals in potassium channels: a mechanism for alternative ion conduction in human Kir3.2 channel mutations.

Mixed SYGnals in potassium channels: a mechanism for alternative ion conduction in human Kir3.2 channel mutations.

Journal: The Journal of physiology

Published: December 30, 2021

Decoding the effects of SGLT2 inhibitors on cardiac arrhythmias in heart failure.

Decoding the effects of SGLT2 inhibitors on cardiac arrhythmias in heart failure.

Journal: European heart journal

Published: August 27, 2021

Showing 1-12 of 59

Last Updated: 09/26/2026