Peter Keane

Birmingham, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 18 publications

Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1.

Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1.

Journal: iScience

Published: October 23, 2023

Chromatin priming elements direct tissue-specific gene activity before hematopoietic specification.

Chromatin priming elements direct tissue-specific gene activity before hematopoietic specification.

Journal: Life science alliance

Published: September 11, 2023

Gene regulation in t(6;9) DEK::NUP214 Acute Myeloid Leukemia resembles that of FLT3-ITD/NPM1 Acute Myeloid Leukemia but with an altered HOX/MEIS axis.

Gene regulation in t(6;9) DEK::NUP214 Acute Myeloid Leukemia resembles that of FLT3-ITD/NPM1 Acute Myeloid Leukemia but with an altered HOX/MEIS axis.

Journal: Leukemia

Published: August 21, 2023

A heterozygous CEBPA mutation disrupting the bZIP domain in a RUNX1 and SRSF2 mutational background causes MDS disease progression.

A heterozygous CEBPA mutation disrupting the bZIP domain in a RUNX1 and SRSF2 mutational background causes MDS disease progression.

Journal: Nature communications

Published: August 02, 2023

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.

Journal: bioRxiv : the preprint server for biology

Published: July 28, 2023

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.

Journal: Cell reports

Published: July 13, 2023

Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth.

Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth.

Journal: Nature communications

Published: May 02, 2023

Identification and interrogation of the gene regulatory network of CEBPA-double mutant acute myeloid leukemia.

Identification and interrogation of the gene regulatory network of CEBPA-double mutant acute myeloid leukemia.

Journal: Leukemia

Published: June 17, 2022

Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia.

Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia.

Journal: Blood

Published: December 03, 2021

Stable Epigenetic Programming of Effector and Central Memory CD4 T Cells Occurs Within 7 Days of Antigen Exposure In Vivo.

Stable Epigenetic Programming of Effector and Central Memory CD4 T Cells Occurs Within 7 Days of Antigen Exposure In Vivo.

Journal: Frontiers in immunology

Published: December 16, 2020

Different mutant RUNX1 oncoproteins program alternate haematopoietic differentiation trajectories.

Different mutant RUNX1 oncoproteins program alternate haematopoietic differentiation trajectories.

Journal: Life science alliance

Published: July 29, 2020

IL-2/IL-7-inducible factors pioneer the path to T cell differentiation in advance of lineage-defining factors.

IL-2/IL-7-inducible factors pioneer the path to T cell differentiation in advance of lineage-defining factors.

Journal: The EMBO journal

Published: April 08, 2020

Showing 1-12 of 18

Last Updated: 09/26/2026