Last Updated: 09/26/2026
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Found 95 publications
Discovery and Optimization of a WRN Helicase Inhibitor Series through Structure-Guided Drug Design from a Covalent Fragment Binding Insight.
Journal: Journal of medicinal chemistry
Published: February 09, 2026
Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance.
Journal: Cancer research
Published: January 24, 2023
Combinations with Allosteric SHP2 Inhibitor TNO155 to Block Receptor Tyrosine Kinase Signaling.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: July 12, 2020
LXH254, a Potent and Selective ARAF-Sparing Inhibitor of BRAF and CRAF for the Treatment of MAPK-Driven Tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: July 02, 2020
Phase II Study of AZD4547 in Patients With Tumors Harboring Aberrations in the FGFR Pathway: Results From the NCI-MATCH Trial (EAY131) Subprotocol W.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Published: May 29, 2020
Inhibition of MDM2 Promotes Antitumor Responses in p53 Wild-Type Cancer Cells through Their Interaction with the Immune and Stromal Microenvironment.
Journal: Cancer research
Published: January 21, 2020
Dynamic single-cell RNA sequencing identifies immunotherapy persister cells following PD-1 blockade.
Dynamic single-cell RNA sequencing identifies immunotherapy persister cells following PD-1 blockade.
Journal: The Journal of clinical investigation
Published: November 15, 2019
Author Correction: LKB1 loss links serine metabolism to DNA methylation and tumorigenesis.
Journal: Nature
Published: November 07, 2019
Last Updated: 09/26/2026