Last Updated: 09/26/2026
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Found 57 publications
Pyruvate Dehydrogenase Complex Stimulation With Dichloroacetate May Improve Septic Cardiac Dysfunction.
Journal: Shock (Augusta, Ga.)
Published: October 31, 2025
Should the "mitochondrial cocktail" be a default option? An opinion.
Journal: Molecular genetics and metabolism
Published: October 29, 2025
The pyruvate dehydrogenase complex at the epigenetic crossroads of acetylation and lactylation.
Journal: Molecular genetics and metabolism
Published: February 22, 2024
Clinical physiology and pharmacology of GSTZ1/MAAI.
Journal: Biochemical pharmacology
Published: July 06, 2023
In-vivo magnetic resonance spectroscopy of lactate as a non-invasive biomarker of dichloroacetate activity in cancer and non-cancer central nervous system disorders.
Journal: Frontiers in oncology
Published: October 25, 2022
The pyruvate dehydrogenase complex: Life's essential, vulnerable and druggable energy homeostat.
Journal: Mitochondrion
Published: August 02, 2022
Sepsis, pyruvate, and mitochondria energy supply chain shortage.
Journal: Journal of leukocyte biology
Published: March 14, 2022
Sodium dichloroacetate stimulates cardiac mitochondrial metabolism and improves cardiac conduction in the ovine fetus during labor.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology
Published: December 01, 2021
Dichloroacetate improves systemic energy balance and feeding behavior during sepsis.
Journal: JCI insight
Published: August 11, 2021
Pharmacokinetic and Biochemical Profiling of Sodium Dichloroacetate in Pregnant Ewes and Fetuses.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: December 07, 2020
Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction.
Journal: eLife
Published: November 04, 2020
Last Updated: 09/26/2026