Petr Dzubak

Palacky University And University Hospital Olomouc Hnevotinska 5 Olomouc 775 20 Czech Republic
Olomouc, 77520, Czech Republic

Last Updated: 09/26/2026

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Found 115 publications

Click chemistry-based synthesis of fluorescent digitoxin derivatives with anticancer activity and cellular imaging potential.

Click chemistry-based synthesis of fluorescent digitoxin derivatives with anticancer activity and cellular imaging potential.

Journal: RSC advances

Published: May 01, 2026

New 1,2,3-Triazole Hybrids as Anticancer Agents: Design, Synthesis, Characterization, and In Silico Studies.

New 1,2,3-Triazole Hybrids as Anticancer Agents: Design, Synthesis, Characterization, and In Silico Studies.

Journal: ChemMedChem

Published: February 06, 2026

Synthesis and Biological Activity of 2,6-Disubstituted and 2,6,9-Trisubstituted 7-Deazapurine Nucleobases.

Synthesis and Biological Activity of 2,6-Disubstituted and 2,6,9-Trisubstituted 7-Deazapurine Nucleobases.

Journal: ChemMedChem

Published: December 19, 2025

Cytotoxicity and antimicrobial activity of platinum(II) complexes based on the ligand precursor 2-phenyl-6-(1,2,3-triazol-4-yl)pyridine - influence of substituent and ancillary ligand on selectivity and activity.

Cytotoxicity and antimicrobial activity of platinum(II) complexes based on the ligand precursor 2-phenyl-6-(1,2,3-triazol-4-yl)pyridine - influence of substituent and ancillary ligand on selectivity and activity.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences

Published: November 04, 2025

Design, synthesis, and biological evaluation of novel 3-oxo-2,3-dihydropyridazine derivatives as interleukin-2-inducible T-cell kinase (ITK) inhibitors.

Design, synthesis, and biological evaluation of novel 3-oxo-2,3-dihydropyridazine derivatives as interleukin-2-inducible T-cell kinase (ITK) inhibitors.

Journal: RSC advances

Published: September 02, 2025

Synthesis and biological evaluation of novel C-30 modified lupane triterpenoids selectively cytotoxic against cancer cells.

Synthesis and biological evaluation of novel C-30 modified lupane triterpenoids selectively cytotoxic against cancer cells.

Journal: European journal of medicinal chemistry

Published: August 29, 2025

Autophagy revealed as a targetable vulnerability in senescent cells by cell painting phenotypic profiling: a mechanistic study of MCOPPB and related compounds.

Autophagy revealed as a targetable vulnerability in senescent cells by cell painting phenotypic profiling: a mechanistic study of MCOPPB and related compounds.

Journal: GeroScience

Published: August 07, 2025

New Derivatives of Caracasine Acid with Anti-Leukemic Activity and Limited Effectiveness in Spheroid Cultures.

New Derivatives of Caracasine Acid with Anti-Leukemic Activity and Limited Effectiveness in Spheroid Cultures.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: June 13, 2025

Synthesis and evaluation of cyclobut-3-ene-1,2-dione-3-hydrazones with benzothiazole moiety as novel anticancer agents inducing nonapoptotic oncosis-like cell death.

Synthesis and evaluation of cyclobut-3-ene-1,2-dione-3-hydrazones with benzothiazole moiety as novel anticancer agents inducing nonapoptotic oncosis-like cell death.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: February 17, 2025

Colchicine-BODIPY Probes: Evidence for the Involvement of Intracellular Membranes in the Targeting of Colchicine to Tubulin.

Colchicine-BODIPY Probes: Evidence for the Involvement of Intracellular Membranes in the Targeting of Colchicine to Tubulin.

Journal: ACS pharmacology & translational science

Published: December 16, 2024

Identification of a novel Azaspirooxindolinone-based PROTAC for selective BTK degradation and enhanced anticancer activity.

Identification of a novel Azaspirooxindolinone-based PROTAC for selective BTK degradation and enhanced anticancer activity.

Journal: Bioorganic chemistry

Published: November 27, 2024

Triterpenoid phthalimides as selective anti-cancer agents targeting mitochondrial apoptosis.

Triterpenoid phthalimides as selective anti-cancer agents targeting mitochondrial apoptosis.

Journal: European journal of medicinal chemistry

Published: November 01, 2024

Showing 1-12 of 115

Last Updated: 09/26/2026