Philip A. Botham
Jealott's Hill
Hill, ENG, United Kingdom
Hill, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 25 publications
Framework for classifying chemicals for repeat dose toxicity using NAMs.
Journal: Archives of toxicology
Published: February 25, 2025
Considerations for the development of guidance on dose level selection for developmental and reproductive toxicity studies.
Journal: Regulatory toxicology and pharmacology : RTP
Published: January 04, 2024
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny - Part IV: the ECETOC and CLE Proposal for a Thyroid Function-Related Neurodevelopmental Toxicity Testing and Assessment Scheme (Thyroid-NDT-TAS).
Journal: Critical reviews in toxicology
Published: August 09, 2023
Analysis of health concerns not addressed by REACH for low tonnage chemicals and opportunities for new approach methodology.
Journal: Archives of toxicology
Published: July 20, 2023
Applying genomics in regulatory toxicology: a report of the ECETOC workshop on omics threshold on non-adversity.
Journal: Archives of toxicology
Published: January 23, 2023
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny-part III: how is substance-mediated thyroid hormone imbalance in pregnant/lactating rats or their progeny related to neurodevelopmental effects?
Journal: Critical reviews in toxicology
Published: December 15, 2022
Assessing chemical carcinogenicity: hazard identification, classification, and risk assessment. Insight from a Toxicology Forum state-of-the-science workshop.
Journal: Critical reviews in toxicology
Published: March 03, 2022
A framework for chemical safety assessment incorporating new approach methodologies within REACH.
Journal: Archives of toxicology
Published: October 11, 2021
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny - part II: how can key events of relevant adverse outcome pathways be addressed in toxicological assessments?
Journal: Critical reviews in toxicology
Published: June 02, 2021
Toward a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny - part I: which parameters from human studies are most relevant for toxicological assessments?
Journal: Critical reviews in toxicology
Published: December 11, 2020
Integration of paraquat pharmacokinetic data across species using PBPK modelling.
Journal: Toxicology and applied pharmacology
Published: September 24, 2020
Paraquat pharmacokinetics in primates and extrapolation to humans.
Journal: Toxicology and applied pharmacology
Published: September 24, 2020
Last Updated: 09/26/2026