Philip C. Biggin

South Parks Road
Oxford, ENG, United Kingdom

Last Updated: 09/26/2026

Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 131 publications

Author Correction: Structural basis for prostaglandin and drug transport via SLCO2A1.

Author Correction: Structural basis for prostaglandin and drug transport via SLCO2A1.

Journal: Nature communications
Published: August 17, 2026

A cannabidiol-sensitive region involved in the allosteric modulation of the α7 nicotinic receptor.

A cannabidiol-sensitive region involved in the allosteric modulation of the α7 nicotinic receptor.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: June 15, 2026

Umbrella Sampling Workflows for Fast-Converging PMF Calculations without Artificial WHAM Constraints.

Umbrella Sampling Workflows for Fast-Converging PMF Calculations without Artificial WHAM Constraints.

Journal: Journal of chemical theory and computation
Published: May 06, 2026

Structural basis for domain coupling in heteromeric glycine receptors revealed by an atypical allosteric agonist.

Structural basis for domain coupling in heteromeric glycine receptors revealed by an atypical allosteric agonist.

Journal: Science advances
Published: February 13, 2026

Advanced Computational Methods in Protein Simulations: A Case Study of Enhanced Sampling Applied to Membrane Transporters.

Advanced Computational Methods in Protein Simulations: A Case Study of Enhanced Sampling Applied to Membrane Transporters.

Journal: Advances in experimental medicine and biology
Published: February 06, 2026

Can AI-Predicted Complexes Teach Machine Learning to Compute Drug Binding Affinity?

Can AI-Predicted Complexes Teach Machine Learning to Compute Drug Binding Affinity?

Journal: Journal of chemical information and modeling
Published: December 10, 2025

Allosteric switching of Ca2+ permeability in the lysosomal ion channel TPC2 underpins biased agonist activation.

Allosteric switching of Ca2+ permeability in the lysosomal ion channel TPC2 underpins biased agonist activation.

Journal: The EMBO journal
Published: November 03, 2025

Asymmetric gating of a homopentameric ion channel GLIC revealed by cryo-EM.

Asymmetric gating of a homopentameric ion channel GLIC revealed by cryo-EM.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: October 23, 2025

Structural basis for pH-responsive amino acid transport via SLC7A4.

Structural basis for pH-responsive amino acid transport via SLC7A4.

Journal: Nature communications
Published: September 26, 2025

Structural determinants for GPCR-mediated inhibition of TASK K2P channels by diacylglycerol and its dysfunction in disease.

Structural determinants for GPCR-mediated inhibition of TASK K2P channels by diacylglycerol and its dysfunction in disease.

Journal: The EMBO journal
Published: August 07, 2025

Steric control of signaling bias in the immunometabolic receptor GPR84.

Steric control of signaling bias in the immunometabolic receptor GPR84.

Journal: bioRxiv : the preprint server for biology
Published: August 06, 2025

Structure-activity relationships can be directly extracted from high-throughput crystallographic evaluation of fragment elaborations in crude reaction mixtures.

Structure-activity relationships can be directly extracted from high-throughput crystallographic evaluation of fragment elaborations in crude reaction mixtures.

Journal: Chemical science
Published: July 03, 2025
Showing 1-12 of 131

Last Updated: 09/26/2026