Last Updated: 09/26/2026
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Found 93 publications
Dysregulated expression of the tumor suppressor p14ARF in cancer provides an effective target for TCR-T cell therapeutics.
Journal: Journal for immunotherapy of cancer
Published: January 21, 2026
A TGF-βR/IL-2R immunomodulatory fusion protein transforms immunosuppression into T cell activation to enhance adoptive T cell therapy.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: September 23, 2025
Triple checkpoint blockade of PD-1, Tim-3, and Lag-3 enhances adoptive T cell immunotherapy in a mouse model of ovarian cancer.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: September 22, 2025
The ubiquitin ligase KLHL6 drives resistance to CD8+ T cell dysfunction.
Journal: Nature
Published: August 29, 2025
Intentional heterogeneity in autologous cell-based gene therapies: strategic considerations for first-in-human trials.
Journal: Journal for immunotherapy of cancer
Published: May 14, 2025
Pancreatic cancer-restricted cryptic antigens are targets for T cell recognition.
Journal: Science (New York, N.Y.)
Published: May 08, 2025
APMAT analysis reveals the association between CD8 T cell receptors, cognate antigen, and T cell phenotype and persistence.
Journal: bioRxiv : the preprint server for biology
Published: January 20, 2025
Acute Myeloid Leukemia Skews Therapeutic WT1-specific CD8 TCR-T Cells Towards an NK-like Phenotype that Compromises Function and Persistence.
Journal: medRxiv : the preprint server for health sciences
Published: January 07, 2025
Antigen-Specific T Cell Receptor Discovery for Treating Progressive Multifocal Leukoencephalopathy.
Journal: bioRxiv : the preprint server for biology
Published: November 22, 2024
Overcoming immune evasion from post-translational modification of a mutant KRAS epitope to achieve TCR-T cell-mediated antitumor activity.
Journal: bioRxiv : the preprint server for biology
Published: September 30, 2024
Last Updated: 09/26/2026