Philip H. Choi

Oncology
1275 York Ave
New York, NY 10065

Last Updated: 09/26/2026

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Found 15 publications

Distinct ERK and PI3K dependencies mediate a heterogeneous response to RAS(ON) inhibition in KRAS-mutant colorectal cancer.

Distinct ERK and PI3K dependencies mediate a heterogeneous response to RAS(ON) inhibition in KRAS-mutant colorectal cancer.

Journal: Cell reports
Published: November 22, 2025

Paired primary-metastasis patient-derived organoids and mouse models identify phenotypic evolution and druggable dependencies of peritoneal metastasis from appendiceal cancer.

Paired primary-metastasis patient-derived organoids and mouse models identify phenotypic evolution and druggable dependencies of peritoneal metastasis from appendiceal cancer.

Journal: bioRxiv : the preprint server for biology
Published: March 03, 2025

An appendiceal cancer organoid biobank identifies phenotypic evolution and druggable dependencies of peritoneal carcinomatosis.

An appendiceal cancer organoid biobank identifies phenotypic evolution and druggable dependencies of peritoneal carcinomatosis.

Journal: Developmental cell
Published: February 07, 2025

Combined inhibition of KRASG12C and mTORC1 kinase is synergistic in non-small cell lung cancer.

Combined inhibition of KRASG12C and mTORC1 kinase is synergistic in non-small cell lung cancer.

Journal: Nature communications
Published: December 21, 2023

Author Correction: CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.

Author Correction: CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.

Journal: Nature communications
Published: November 17, 2022

CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.

CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.

Journal: Nature communications
Published: May 30, 2022

A Rationally Designed c-di-AMP Förster Resonance Energy Transfer Biosensor To Monitor Nucleotide Dynamics.

A Rationally Designed c-di-AMP Förster Resonance Energy Transfer Biosensor To Monitor Nucleotide Dynamics.

Journal: Journal of bacteriology
Published: July 26, 2021

Crystal structure of a thermophilic fungal cyanase and its implications on the catalytic mechanism for bioremediation.

Crystal structure of a thermophilic fungal cyanase and its implications on the catalytic mechanism for bioremediation.

Journal: Scientific reports
Published: March 27, 2020

Structural and functional studies of pyruvate carboxylase regulation by cyclic di-AMP in lactic acid bacteria.

Structural and functional studies of pyruvate carboxylase regulation by cyclic di-AMP in lactic acid bacteria.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: August 16, 2017

c-di-AMP modulates Listeria monocytogenes central metabolism to regulate growth, antibiotic resistance and osmoregulation.

c-di-AMP modulates Listeria monocytogenes central metabolism to regulate growth, antibiotic resistance and osmoregulation.

Journal: Molecular microbiology
Published: January 14, 2017

Cyclic di-AMP targets the cystathionine beta-synthase domain of the osmolyte transporter OpuC.

Cyclic di-AMP targets the cystathionine beta-synthase domain of the osmolyte transporter OpuC.

Journal: Molecular microbiology
Published: July 01, 2016

A distinct holoenzyme organization for two-subunit pyruvate carboxylase.

A distinct holoenzyme organization for two-subunit pyruvate carboxylase.

Journal: Nature communications
Published: December 26, 2015
Showing 1-12 of 15

Last Updated: 09/26/2026