Philipp Hackert

Goettingen, NI, Germany

Last Updated: 09/26/2026

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Found 19 publications

MDM2 binds and suppresses RNA polymerase III to restrain the innate immune response to cytosolic DNA.

MDM2 binds and suppresses RNA polymerase III to restrain the innate immune response to cytosolic DNA.

Journal: Cell death and differentiation
Published: January 11, 2026

Distinct steps of nuclear maturation of human pre-60S complexes require the activity of GTPases including GNL3L.

Distinct steps of nuclear maturation of human pre-60S complexes require the activity of GTPases including GNL3L.

Journal: Nucleic acids research
Published: September 14, 2025

2'-O-methylation-dependent installation of N2-methylguanosine in the U6 internal stem loop facilitates efficient spliceosome assembly.

2'-O-methylation-dependent installation of N2-methylguanosine in the U6 internal stem loop facilitates efficient spliceosome assembly.

Journal: Nature communications
Published: July 31, 2025

GPATCH4 regulates rRNA and snRNA 2'-O-methylation in both DHX15-dependent and DHX15-independent manners.

GPATCH4 regulates rRNA and snRNA 2'-O-methylation in both DHX15-dependent and DHX15-independent manners.

Journal: Nucleic acids research
Published: August 10, 2023

The RNA methyltransferase METTL8 installs m3C32 in mitochondrial tRNAsThr/Ser(UCN) to optimise tRNA structure and mitochondrial translation.

The RNA methyltransferase METTL8 installs m3C32 in mitochondrial tRNAsThr/Ser(UCN) to optimise tRNA structure and mitochondrial translation.

Journal: Nature communications
Published: May 19, 2021

The RNA helicase Dbp7 promotes domain V/VI compaction and stabilization of inter-domain interactions during early 60S assembly.

The RNA helicase Dbp7 promotes domain V/VI compaction and stabilization of inter-domain interactions during early 60S assembly.

Journal: Nature communications
Published: December 14, 2020

The DExD box ATPase DDX55 is recruited to domain IV of the 28S ribosomal RNA by its C-terminal region.

The DExD box ATPase DDX55 is recruited to domain IV of the 28S ribosomal RNA by its C-terminal region.

Journal: RNA biology
Published: October 13, 2020

RNA helicase-mediated regulation of snoRNP dynamics on pre-ribosomes and rRNA 2'-O-methylation.

RNA helicase-mediated regulation of snoRNP dynamics on pre-ribosomes and rRNA 2'-O-methylation.

Journal: Nucleic acids research
Published: September 01, 2020

Ribosome-bound Get4/5 facilitates the capture of tail-anchored proteins by Sgt2 in yeast.

Ribosome-bound Get4/5 facilitates the capture of tail-anchored proteins by Sgt2 in yeast.

Journal: Nature communications
Published: July 10, 2020

The interaction of DNA repair factors ASCC2 and ASCC3 is affected by somatic cancer mutations.

The interaction of DNA repair factors ASCC2 and ASCC3 is affected by somatic cancer mutations.

Journal: Nature communications
Published: May 13, 2020

Sgd1 is an MIF4G domain-containing cofactor of the RNA helicase Fal1 and associates with the 5' domain of the 18S rRNA sequence.

Sgd1 is an MIF4G domain-containing cofactor of the RNA helicase Fal1 and associates with the 5' domain of the 18S rRNA sequence.

Journal: RNA biology
Published: January 30, 2020

Pol5 is required for recycling of small subunit biogenesis factors and for formation of the peptide exit tunnel of the large ribosomal subunit.

Pol5 is required for recycling of small subunit biogenesis factors and for formation of the peptide exit tunnel of the large ribosomal subunit.

Journal: Nucleic acids research
Published: May 24, 2019
Showing 1-12 of 19

Last Updated: 09/26/2026