Philippe Cotelle

Lille, 59000, France

Last Updated: 09/26/2026

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Found 26 publications

Towards the design of ligands of the internal pocket TEADs C-terminal domain.

Towards the design of ligands of the internal pocket TEADs C-terminal domain.

Journal: European journal of medicinal chemistry

Published: September 13, 2024

Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings.

Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings.

Journal: Bioorganic & medicinal chemistry letters

Published: August 04, 2023

Crosstalk between the Hippo Pathway and the Wnt Pathway in Huntington's Disease and Other Neurodegenerative Disorders.

Crosstalk between the Hippo Pathway and the Wnt Pathway in Huntington's Disease and Other Neurodegenerative Disorders.

Journal: Cells

Published: September 13, 2022

Progress with YAP/TAZ-TEAD inhibitors: a patent review (2018-present).

Progress with YAP/TAZ-TEAD inhibitors: a patent review (2018-present).

Journal: Expert opinion on therapeutic patents

Published: June 29, 2022

Toward the Design of Ligands Selective for the C-Terminal Domain of TEADs.

Toward the Design of Ligands Selective for the C-Terminal Domain of TEADs.

Journal: Journal of medicinal chemistry

Published: April 07, 2022

Identification of potent inhibitors of arenavirus and SARS-CoV-2 exoribonucleases by fluorescence polarization assay.

Identification of potent inhibitors of arenavirus and SARS-CoV-2 exoribonucleases by fluorescence polarization assay.

Journal: Antiviral research

Published: April 04, 2022

The NSP14/NSP10 RNA repair complex as a Pan-coronavirus therapeutic target.

The NSP14/NSP10 RNA repair complex as a Pan-coronavirus therapeutic target.

Journal: Cell death and differentiation

Published: August 27, 2021

Discovery of a cryptic site at the interface 2 of TEAD - Towards a new family of YAP/TAZ-TEAD inhibitors.

Discovery of a cryptic site at the interface 2 of TEAD - Towards a new family of YAP/TAZ-TEAD inhibitors.

Journal: European journal of medicinal chemistry

Published: July 02, 2021

Design, Synthesis and Evaluation of a Series of 1,5-Diaryl-1,2,3-triazole-4-carbohydrazones as Inhibitors of the YAP-TAZ/TEAD Complex.

Design, Synthesis and Evaluation of a Series of 1,5-Diaryl-1,2,3-triazole-4-carbohydrazones as Inhibitors of the YAP-TAZ/TEAD Complex.

Journal: ChemMedChem

Published: March 03, 2021

Metal chelators for the inhibition of the lymphocytic choriomeningitis virus endonuclease domain.

Metal chelators for the inhibition of the lymphocytic choriomeningitis virus endonuclease domain.

Journal: Antiviral research

Published: May 25, 2018

Toward the Discovery of a Novel Class of YAP⁻TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP⁻TEAD Protein⁻Protein Interface.

Toward the Discovery of a Novel Class of YAP⁻TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP⁻TEAD Protein⁻Protein Interface.

Journal: Cancers

Published: April 24, 2018

Targeting Transcriptional Enhanced Associate Domains (TEADs).

Targeting Transcriptional Enhanced Associate Domains (TEADs).

Journal: Journal of medicinal chemistry

Published: December 19, 2017

Showing 1-12 of 26

Last Updated: 09/26/2026