Last Updated: 09/26/2026
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Found 9 publications
Discovery of N-(3-fluorophenyl)-2-(4-((7-(1-methyl-1H-pyrazol-4-yl)quinazolin-4-yl)amino)phenyl)acetamide as the first orally active selective aurora kinase B inhibitor.
Journal: European journal of medicinal chemistry
Published: July 04, 2024
Mi-2β promotes immune evasion in melanoma by activating EZH2 methylation.
Journal: Nature communications
Published: October 18, 2023
An imidazo[1,2-a]pyridine-pyridine derivative potently inhibits FLT3-ITD and FLT3-ITD secondary mutants, including gilteritinib-resistant FLT3-ITD/F691L.
Journal: European journal of medicinal chemistry
Published: May 21, 2023
Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose.
Journal: Journal of medicinal chemistry
Published: January 27, 2022
3-Aminophthalic acid, a new cereblon ligand for targeted protein degradation by O'PROTAC.
Journal: Chemical communications (Cambridge, England)
Published: January 26, 2022
Delivery of Oligonucleotides: Efficiency with Lipid Conjugation and Clinical Outcome.
Journal: Pharmaceutics
Published: December 29, 2021
Discovery of 4-aminoquinolines as highly selective TGFβR1 inhibitors with an attenuated MAP4K4 profile for potential applications in immuno-oncology.
Journal: European journal of medicinal chemistry
Published: July 06, 2021
Discovery and biological evaluation of phthalazines as novel non-kinase TGFβ pathway inhibitors.
Journal: European journal of medicinal chemistry
Published: May 15, 2021
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Last Updated: 09/26/2026