Pierre Chapdelaine

Quebec, QC, Canada

Last Updated: 09/26/2026

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Found 13 publications

Increased Frataxin Expression Induced in Friedreich Ataxia Cells by Platinum TALE-VP64s or Platinum TALE-SunTag.

Increased Frataxin Expression Induced in Friedreich Ataxia Cells by Platinum TALE-VP64s or Platinum TALE-SunTag.

Journal: Molecular therapy. Nucleic acids
Published: March 28, 2018

Efficient Restoration of the Dystrophin Gene Reading Frame and Protein Structure in DMD Myoblasts Using the CinDel Method.

Efficient Restoration of the Dystrophin Gene Reading Frame and Protein Structure in DMD Myoblasts Using the CinDel Method.

Journal: Molecular therapy. Nucleic acids
Published: December 10, 2015

Development of an AAV9 coding for a 3XFLAG-TALEfrat#8-VP64 able to increase in vivo the human frataxin in YG8R mice.

Development of an AAV9 coding for a 3XFLAG-TALEfrat#8-VP64 able to increase in vivo the human frataxin in YG8R mice.

Journal: Gene therapy
Published: November 22, 2015

Characterization of frataxin gene network in Friedreich's ataxia fibroblasts using the RNA-Seq technique.

Characterization of frataxin gene network in Friedreich's ataxia fibroblasts using the RNA-Seq technique.

Journal: Mitochondrion
Published: November 17, 2015

Generation of human endometrial knockout cell lines with the CRISPR/Cas9 system confirms the prostaglandin F2α synthase activity of aldo-ketoreductase 1B1.

Generation of human endometrial knockout cell lines with the CRISPR/Cas9 system confirms the prostaglandin F2α synthase activity of aldo-ketoreductase 1B1.

Journal: Molecular human reproduction
Published: March 29, 2014

An AAV9 coding for frataxin clearly improved the symptoms and prolonged the life of Friedreich ataxia mouse models.

An AAV9 coding for frataxin clearly improved the symptoms and prolonged the life of Friedreich ataxia mouse models.

Journal: Molecular therapy. Methods & clinical development
Published: January 01, 2014

A Potential New Therapeutic Approach for Friedreich Ataxia: Induction of Frataxin Expression With TALE Proteins.

A Potential New Therapeutic Approach for Friedreich Ataxia: Induction of Frataxin Expression With TALE Proteins.

Journal: Molecular therapy. Nucleic acids
Published: May 29, 2013

Evaluation of the prostaglandin F synthase activity of human and bovine aldo-keto reductases: AKR1A1s complement AKR1B1s as potent PGF synthases.

Evaluation of the prostaglandin F synthase activity of human and bovine aldo-keto reductases: AKR1A1s complement AKR1B1s as potent PGF synthases.

Journal: Prostaglandins & other lipid mediators
Published: February 27, 2013

Targeted Gene Addition of Microdystrophin in Mice Skeletal Muscle via Human Myoblast Transplantation.

Targeted Gene Addition of Microdystrophin in Mice Skeletal Muscle via Human Myoblast Transplantation.

Journal: Molecular therapy. Nucleic acids
Published: January 31, 2013

Transcription activator-like effector proteins induce the expression of the frataxin gene.

Transcription activator-like effector proteins induce the expression of the frataxin gene.

Journal: Human gene therapy
Published: May 17, 2012

The Prostaglandin F Synthase Activity of the Human Aldose Reductase AKR1B1 Brings New Lenses to Look at Pathologic Conditions.

The Prostaglandin F Synthase Activity of the Human Aldose Reductase AKR1B1 Brings New Lenses to Look at Pathologic Conditions.

Journal: Frontiers in pharmacology
Published: March 01, 2012

The multidrug resistance-associated protein 4 (MRP4) appears as a functional carrier of prostaglandins regulated by oxytocin in the bovine endometrium.

The multidrug resistance-associated protein 4 (MRP4) appears as a functional carrier of prostaglandins regulated by oxytocin in the bovine endometrium.

Journal: Endocrinology
Published: October 13, 2011
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Last Updated: 09/26/2026