Pierre Francotte

Liege, WAL, Belgium

Last Updated: 09/26/2026

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Found 34 publications

Kainate Receptor Allosteric Modulators: State of the Art and Future Directions.

Kainate Receptor Allosteric Modulators: State of the Art and Future Directions.

Journal: ChemMedChem

Published: February 18, 2026

Structural Exploration around 4-Cyclopropyl-Substituted 1,2,4-Benzothiadiazine 1,1-Dioxides: Impact of the Dihalo-Substitution of the Benzene Ring on α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid (AMPA) Receptor Potentiation.

Structural Exploration around 4-Cyclopropyl-Substituted 1,2,4-Benzothiadiazine 1,1-Dioxides: Impact of the Dihalo-Substitution of the Benzene Ring on α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid (AMPA) Receptor Potentiation.

Journal: Journal of medicinal chemistry

Published: September 02, 2025

2-Oxo-2H-chromen-7-yl 3-methyl-butano-ate.

2-Oxo-2H-chromen-7-yl 3-methyl-butano-ate.

Journal: IUCrData

Published: January 13, 2025

Trifluoromethylcinnamanilides - Effective dual inhibitors of Mycobacterium smegmatis and Plasmodium falciparum.

Trifluoromethylcinnamanilides - Effective dual inhibitors of Mycobacterium smegmatis and Plasmodium falciparum.

Journal: Bioorganic chemistry

Published: September 24, 2024

Surface enhanced transmission Raman spectroscopy: Quantitative performances for impurity analysis in complex matrices.

Surface enhanced transmission Raman spectroscopy: Quantitative performances for impurity analysis in complex matrices.

Journal: Journal of pharmaceutical and biomedical analysis

Published: July 21, 2024

Optimisation of a Microwave Synthesis of Silver Nanoparticles by a Quality by Design Approach to Improve SERS Analytical Performances.

Optimisation of a Microwave Synthesis of Silver Nanoparticles by a Quality by Design Approach to Improve SERS Analytical Performances.

Journal: Molecules (Basel, Switzerland)

Published: May 17, 2024

Synthesis, structure and Hirshfeld surface analysis of 2-oxo-2H-chromen-4-yl penta-noate.

Synthesis, structure and Hirshfeld surface analysis of 2-oxo-2H-chromen-4-yl penta-noate.

Journal: Acta crystallographica. Section E, Crystallographic communications

Published: April 26, 2024

Crystal structure of the GluK1 ligand-binding domain with kainate and the full-spanning positive allosteric modulator BPAM538.

Crystal structure of the GluK1 ligand-binding domain with kainate and the full-spanning positive allosteric modulator BPAM538.

Journal: Journal of structural biology

Published: November 20, 2023

The positive allosteric modulator BPAM344 and L-glutamate introduce an active-like structure of the ligand-binding domain of GluK2.

The positive allosteric modulator BPAM344 and L-glutamate introduce an active-like structure of the ligand-binding domain of GluK2.

Journal: FEBS letters

Published: November 16, 2023

Exploring thienothiadiazine dioxides as isosteric analogues of benzo- and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators.

Exploring thienothiadiazine dioxides as isosteric analogues of benzo- and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators.

Journal: European journal of medicinal chemistry

Published: October 24, 2023

Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure.

Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure.

Journal: The FEBS journal

Published: July 06, 2023

Targeting Myeloperoxidase Activity and Neutrophil ROS Production to Modulate Redox Process: Effect of Ellagic Acid and Analogues.

Targeting Myeloperoxidase Activity and Neutrophil ROS Production to Modulate Redox Process: Effect of Ellagic Acid and Analogues.

Journal: Molecules (Basel, Switzerland)

Published: April 13, 2023

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Last Updated: 09/26/2026