Pinar Akcakaya
BioPharmaceuticals R&D Unit, AstraZeneca
Goeteborg, O, Sweden
Goeteborg, O, Sweden
Last Updated: 09/26/2026
Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 20 publications
Single-cell and in vivo profiling reveal heterogeneous and organ-specific CRISPR-Cas9 off-target and translocation outcomes.
Journal: Nature communications
Published: April 03, 2026
Engineered PsCas9 enables therapeutic genome editing in mouse liver with lipid nanoparticles.
Journal: Nature communications
Published: February 28, 2024
Customizable virus-like particles deliver CRISPR-Cas9 ribonucleoprotein for effective ocular neovascular and Huntington's disease gene therapy.
Journal: Nature nanotechnology
Published: September 28, 2023
Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing.
Journal: Nature communications
Published: January 26, 2023
A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo.
A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo.
Journal: Nature communications
Published: October 03, 2022
Imatinib Regulates miR-483-3p and Mitochondrial Respiratory Complexes in Gastrointestinal Stromal Tumors.
Journal: International journal of molecular sciences
Published: May 12, 2021
Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: July 12, 2020
Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq.
Journal: Science (New York, N.Y.)
Published: November 08, 2018
In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model.
Journal: BMC biology
Published: October 22, 2018
miR-125a-5p regulation increases phosphorylation of FAK that contributes to imatinib resistance in gastrointestinal stromal tumors.
Journal: Experimental cell research
Published: April 18, 2018
In vivo CRISPR editing with no detectable genome-wide off-target mutations.
Journal: Nature
Published: February 27, 2018
MicroRNAs and Gastrointestinal Stromal Tumor.
Journal: Advances in experimental medicine and biology
Published: December 15, 2015
Last Updated: 09/26/2026