Pirjo M. Laakkonen

Helsinki, 00014, Finland

Last Updated: 09/26/2026

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Found 51 publications

Intracranial Human BT12 Glioblastoma Xenograft is [18F]FET PET Negative but 6-[18F]Fluoronicotinic Acid PET Positive: Exploring a Novel Approach for Clinical Glioblastoma Imaging.

Intracranial Human BT12 Glioblastoma Xenograft is [18F]FET PET Negative but 6-[18F]Fluoronicotinic Acid PET Positive: Exploring a Novel Approach for Clinical Glioblastoma Imaging.

Journal: Molecular pharmaceutics

Published: June 09, 2026

Differential cytotoxic effect of polybrene on distinct glioblastoma subtypes.

Differential cytotoxic effect of polybrene on distinct glioblastoma subtypes.

Journal: Neuroscience

Published: January 28, 2026

Differential cytotoxic effect of polybrene on distinct glioblastoma subtypes.

Differential cytotoxic effect of polybrene on distinct glioblastoma subtypes.

Journal: Neuroscience

Published: January 28, 2026

Glioblastoma cells utilize evolutionarily adapted cell metabolism to promote their malignant proliferation.

Glioblastoma cells utilize evolutionarily adapted cell metabolism to promote their malignant proliferation.

Journal: Acta neuropathologica communications

Published: December 04, 2025

Combining an anti-HER2 antibody-drug conjugate with an anti-nectin-4 antibody-drug conjugate enhances efficacy in breast cancer and gastric cancer models.

Combining an anti-HER2 antibody-drug conjugate with an anti-nectin-4 antibody-drug conjugate enhances efficacy in breast cancer and gastric cancer models.

Journal: Cancer cell international

Published: July 04, 2025

Utilizing Monocarboxylate Transporter 1-Mediated Blood-Brain Barrier Penetration for Glioblastoma Positron Emission Tomography Imaging with 6-[18F]Fluoronicotinic Acid.

Utilizing Monocarboxylate Transporter 1-Mediated Blood-Brain Barrier Penetration for Glioblastoma Positron Emission Tomography Imaging with 6-[18F]Fluoronicotinic Acid.

Journal: Molecular pharmaceutics

Published: July 03, 2025

Therapeutic Reprogramming of Glioblastoma Phenotypic States Using Multifunctional Heparin Nanoparticles.

Therapeutic Reprogramming of Glioblastoma Phenotypic States Using Multifunctional Heparin Nanoparticles.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: May 28, 2025

Rapid cleavage of 6-[18F]fluoronicotinic acid prosthetic group governs BT12 glioblastoma xenograft uptake: implications for radiolabeling design of biomolecules.

Rapid cleavage of 6-[18F]fluoronicotinic acid prosthetic group governs BT12 glioblastoma xenograft uptake: implications for radiolabeling design of biomolecules.

Journal: EJNMMI radiopharmacy and chemistry

Published: May 09, 2025

Drug-tolerant persisting polyploid giant cancer cells mediate resistance to HER2-targeting antibody-drug conjugates.

Drug-tolerant persisting polyploid giant cancer cells mediate resistance to HER2-targeting antibody-drug conjugates.

Journal: Cancer letters

Published: April 28, 2025

Deciphering the Dialogue between Brain Tumors, Neurons, and Astrocytes.

Deciphering the Dialogue between Brain Tumors, Neurons, and Astrocytes.

Journal: The American journal of pathology

Published: December 13, 2024

Disitamab vedotin in preclinical models of HER2-positive breast and gastric cancers resistant to trastuzumab emtansine and trastuzumab deruxtecan.

Disitamab vedotin in preclinical models of HER2-positive breast and gastric cancers resistant to trastuzumab emtansine and trastuzumab deruxtecan.

Journal: Translational oncology

Published: September 20, 2024

Switching the Chemoselectivity in the Preparation of [18F]FNA-N-CooP, a Free Thiol-Containing Peptide for Targeted Positron Emission Tomography Imaging of Fatty Acid Binding Protein 3.

Switching the Chemoselectivity in the Preparation of [18F]FNA-N-CooP, a Free Thiol-Containing Peptide for Targeted Positron Emission Tomography Imaging of Fatty Acid Binding Protein 3.

Journal: Molecular pharmaceutics

Published: July 15, 2024

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Last Updated: 09/26/2026