Last Updated: 09/26/2026
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Found 4 publications
Discovery of Potent, Selective, and State-Dependent NaV1.7 Inhibitors with Robust Oral Efficacy in Pain Models: Structure-Activity Relationship and Optimization of Chroman and Indane Aryl Sulfonamides.
Journal: Journal of medicinal chemistry
Published: May 06, 2020
Design, Synthesis, and Pharmacological Evaluation of 5,6-Disubstituted Pyridin-2(1H)-one Derivatives as Phosphodiesterase 10A (PDE10A) Antagonists.
Journal: Journal of medicinal chemistry
Published: October 01, 2015
Design, synthesis and pharmacological evaluation of novel polycyclic heteroarene ethers as PDE10A inhibitors: part II.
Journal: Bioorganic & medicinal chemistry letters
Published: March 03, 2014
Imidazopyridazinones as novel PDE7 inhibitors: SAR and in vivo studies in Parkinson's disease model.
Imidazopyridazinones as novel PDE7 inhibitors: SAR and in vivo studies in Parkinson's disease model.
Journal: Bioorganic & medicinal chemistry letters
Published: May 04, 2012
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Last Updated: 09/26/2026