Prem N. Yadav

Sector 10, Jankipuram Extension, Sitapur Road
Lucknow, UP 226031, India

Last Updated: 09/26/2026

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Found 39 publications

Modular synthesis and bioevaluation of novel fused-β-carbolines as kappa opioid receptor modulators.

Modular synthesis and bioevaluation of novel fused-β-carbolines as kappa opioid receptor modulators.

Journal: European journal of medicinal chemistry

Published: February 20, 2026

Novel bis(triazole) analogues as selective TGR5 agonists with anti-diabesity effects.

Novel bis(triazole) analogues as selective TGR5 agonists with anti-diabesity effects.

Journal: Bioorganic chemistry

Published: September 26, 2025

Towards next-generation 5-hydroxytryptamine 2C receptor modulators: Greener synthesis and evaluation of novel isocoumarin derivatives as PAAMs of 5-HT2CR.

Towards next-generation 5-hydroxytryptamine 2C receptor modulators: Greener synthesis and evaluation of novel isocoumarin derivatives as PAAMs of 5-HT2CR.

Journal: Bioorganic chemistry

Published: September 03, 2025

Synthesis and Evaluation of Novel Aza-Aromatics as Dual 5‑HT2A and 5‑HT2C Receptor Agonists.

Synthesis and Evaluation of Novel Aza-Aromatics as Dual 5‑HT2A and 5‑HT2C Receptor Agonists.

Journal: ACS medicinal chemistry letters

Published: August 20, 2025

Pharmacological inhibition of IRAK1/4 ameliorates high-fat diet-induced vascular dysfunction and cognitive impairment.

Pharmacological inhibition of IRAK1/4 ameliorates high-fat diet-induced vascular dysfunction and cognitive impairment.

Journal: Molecular biology reports

Published: June 10, 2025

Discovery, preclinical safety, and efficacy characterization of SMAC mimetic S-016-1348 as a potential cancer therapeutic.

Discovery, preclinical safety, and efficacy characterization of SMAC mimetic S-016-1348 as a potential cancer therapeutic.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: April 29, 2025

C‑X‑C Motif Chemokine 10/C-X‑C Motif Chemokine Receptor 3 Signaling Induces Neural Senescence and Cognitive Impairments.

C‑X‑C Motif Chemokine 10/C-X‑C Motif Chemokine Receptor 3 Signaling Induces Neural Senescence and Cognitive Impairments.

Journal: ACS pharmacology & translational science

Published: January 14, 2025

Baicalein isolated from Oroxylum indicum acts as a potent µ- and κ-opioid receptor antagonist agent via the reversal of agonist-mediated cAMP inhibition.

Baicalein isolated from Oroxylum indicum acts as a potent µ- and κ-opioid receptor antagonist agent via the reversal of agonist-mediated cAMP inhibition.

Journal: Natural product research

Published: August 29, 2024

Kappa Opioid Receptor Activation Induces Epigenetic Silencing of Brain-Derived Neurotropic Factor via HDAC5 in Depression.

Kappa Opioid Receptor Activation Induces Epigenetic Silencing of Brain-Derived Neurotropic Factor via HDAC5 in Depression.

Journal: ACS chemical neuroscience

Published: August 27, 2024

Discovery and structure - activity relationships of 2,4,5-trimethoxyphenyl pyrimidine derivatives as selective D5 receptor partial agonists.

Discovery and structure - activity relationships of 2,4,5-trimethoxyphenyl pyrimidine derivatives as selective D5 receptor partial agonists.

Journal: Bioorganic chemistry

Published: July 15, 2024

Molecular mechanism of distinct chemokine engagement and functional divergence of the human Duffy antigen receptor.

Molecular mechanism of distinct chemokine engagement and functional divergence of the human Duffy antigen receptor.

Journal: Cell

Published: September 03, 2023

Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system.

Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system.

Journal: Nature communications

Published: April 11, 2023

Showing 1-12 of 39

Last Updated: 09/26/2026