Prem Ponka

Montreal, QC, Canada

Last Updated: 09/26/2026

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Found 20 publications

Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin.

Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin.

Journal: Nature metabolism
Published: July 06, 2019

Transferrin receptor 1 controls systemic iron homeostasis by fine-tuning hepcidin expression to hepatocellular iron load.

Transferrin receptor 1 controls systemic iron homeostasis by fine-tuning hepcidin expression to hepatocellular iron load.

Journal: Blood
Published: May 09, 2018

Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in a β-thalassemia mouse model.

Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in a β-thalassemia mouse model.

Journal: Blood
Published: July 27, 2017

Do Mammalian Cells Really Need to Export and Import Heme?

Do Mammalian Cells Really Need to Export and Import Heme?

Journal: Trends in biochemical sciences
Published: November 22, 2016

The mouse Char10 locus regulates severity of pyruvate kinase deficiency and susceptibility to malaria.

The mouse Char10 locus regulates severity of pyruvate kinase deficiency and susceptibility to malaria.

Journal: PloS one
Published: November 15, 2016

Decreasing TfR1 expression reverses anemia and hepcidin suppression in β-thalassemic mice.

Decreasing TfR1 expression reverses anemia and hepcidin suppression in β-thalassemic mice.

Journal: Blood
Published: September 26, 2016

Extracellular glycine is necessary for optimal hemoglobinization of erythroid cells.

Extracellular glycine is necessary for optimal hemoglobinization of erythroid cells.

Journal: Haematologica
Published: August 31, 2016

Erythroid cell mitochondria receive endosomal iron by a "kiss-and-run" mechanism.

Erythroid cell mitochondria receive endosomal iron by a "kiss-and-run" mechanism.

Journal: Biochimica et biophysica acta
Published: July 07, 2016

Response to: Dietary and pharmacological factors affecting iron absorption in mice and man.

Response to: Dietary and pharmacological factors affecting iron absorption in mice and man.

Journal: Haematologica
Published: March 02, 2016

Mice are poor heme absorbers and do not require intestinal Hmox1 for dietary heme iron assimilation.

Mice are poor heme absorbers and do not require intestinal Hmox1 for dietary heme iron assimilation.

Journal: Haematologica
Published: May 16, 2015

Thioredoxin-interacting protein regulates the differentiation of murine erythroid precursors.

Thioredoxin-interacting protein regulates the differentiation of murine erythroid precursors.

Journal: Experimental hematology
Published: October 24, 2014

Heme oxygenase 1 is expressed in murine erythroid cells where it controls the level of regulatory heme.

Heme oxygenase 1 is expressed in murine erythroid cells where it controls the level of regulatory heme.

Journal: Blood
Published: February 11, 2014
Showing 1-12 of 20

Last Updated: 09/26/2026