Qiansen Zhang

Shanghai Key Laboratory Of Regulatory Biology
Shanghai, 200241, China

Last Updated: 09/26/2026

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Found 49 publications

Discovery of novel cereblon-recruiting PRMT5 degraders with in vivo efficacy against triple-negative breast cancer.

Discovery of novel cereblon-recruiting PRMT5 degraders with in vivo efficacy against triple-negative breast cancer.

Journal: European journal of medicinal chemistry

Published: May 25, 2026

Structural insights into measles virus RNA synthesis regulation and pan-paramyxoviral polymerase inhibition by ERDRP-0519.

Structural insights into measles virus RNA synthesis regulation and pan-paramyxoviral polymerase inhibition by ERDRP-0519.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: April 06, 2026

Structural mechanisms for self-activation of protease-activated receptor 4 by tethered ligand.

Structural mechanisms for self-activation of protease-activated receptor 4 by tethered ligand.

Journal: Cell reports

Published: November 10, 2025

Exogenous activation of the adhesion GPCR ADGRD1/GPR133 protects against bone loss by negatively regulating osteoclastogenesis.

Exogenous activation of the adhesion GPCR ADGRD1/GPR133 protects against bone loss by negatively regulating osteoclastogenesis.

Journal: Science advances

Published: July 11, 2025

Secondary structure transitions and dual PIP2 binding define cardiac KCNQ1-KCNE1 channel gating.

Secondary structure transitions and dual PIP2 binding define cardiac KCNQ1-KCNE1 channel gating.

Journal: Cell research

Published: May 29, 2025

Hv1 inhibition rescues AD pathology by restoring microglial mitochondrial function and enhancing mitochondrial transfer.

Hv1 inhibition rescues AD pathology by restoring microglial mitochondrial function and enhancing mitochondrial transfer.

Journal: Experimental & molecular medicine

Published: April 01, 2025

Author Correction: The lactate receptor HCAR1 drives the recruitment of immunosuppressive PMN-MDSCs in colorectal cancer.

Author Correction: The lactate receptor HCAR1 drives the recruitment of immunosuppressive PMN-MDSCs in colorectal cancer.

Journal: Nature immunology

Published: March 11, 2025

GPT2-ICC: A data-driven approach for accurate ion channel identification using pre-trained large language models.

GPT2-ICC: A data-driven approach for accurate ion channel identification using pre-trained large language models.

Journal: Journal of pharmaceutical analysis

Published: October 30, 2024

Rational design strategy for thermostability enhancement of protein-glutaminase and investigation of the underlying mechanisms.

Rational design strategy for thermostability enhancement of protein-glutaminase and investigation of the underlying mechanisms.

Journal: International journal of biological macromolecules

Published: October 09, 2024

Small molecule inhibits KCNQ channels with a non-blocking mechanism.

Small molecule inhibits KCNQ channels with a non-blocking mechanism.

Journal: Nature chemical biology

Published: July 30, 2024

Targeting ubiquitin-independent proteasome with small molecule increases susceptibility in pan-KRAS-mutant cancer models.

Targeting ubiquitin-independent proteasome with small molecule increases susceptibility in pan-KRAS-mutant cancer models.

Journal: The Journal of clinical investigation

Published: July 25, 2024

C-type inactivation and proton modulation mechanisms of the TASK3 channel.

C-type inactivation and proton modulation mechanisms of the TASK3 channel.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: April 17, 2024

Showing 1-12 of 49

Last Updated: 09/26/2026